| Type | Description |
|---|---|
| Definition | Sir1p |
| Date | Results | Publications |
|---|---|---|
| 2017-05-27 11:16:00 | silencing requires Sir2, a highly-conserved NAD(+)-dependent histone deacetylase. At locations other than the rDNA, silencing also requires additional Sir proteins, Sir1, Sir3, and Sir4 that together form a repressive heterochromatin-like structure termed silent chromatin. | 27516616 |
| 2016-08-13 10:55:00 | data provide the most complete picture to date of how the earliest SIR1-containing SIR silencing complex functioned and the evolutionary trajectories it may have followed | 26811328 |
| 2010-01-21 00:00:00 | SIR1 plays role in the origin recognition complex dependent silencing for origin firing at silent mating type loci | 16479013 |
| 2010-01-21 00:00:00 | The functional specialization of Sir3,as a silencing protein was facilitated by the tandem duplication of the OIR domain in the Sir1 family, allowing distinct Sir1-Sir3 and Sir1-Orc1 interactions through OIR-BAH domain interactions. | 19171939 |
| 2010-01-21 00:00:00 | The functional duality might contribute to Sir1's selectivity for silencer-bound origin recognition complex in vivo. | 19029247 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SIR1_YEAST
UniprotKB:
P21691
UniParc:
UPI000193281A
EMBL:
M38524,
Z28326,
BK006944
EnsemblGenome:
YKR101W
KO:
sce:YKR101W
|
| Nucleutide sequences |
EMBL-CDS:
DAA09252.1,
AAA35046.1,
CAA82181.1
EnsemblGenome_TRS:
YKR101W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YKR101W
RefSeq:
NP_013027.4
|
| Others |
UniRef100:
UniRef100_P21691
UniRef90:
UniRef90_P21691
UniRef50:
UniRef50_P21691
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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