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853961 PRP16

853961

PRP16

DEAH-box RNA helicase PRP16

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition DEAH-box RNA helicase PRP16

研究结论

Date Results Publications
2017-09-09 13:29:00 In the process of pre-mRNA splicing, Cwc25 binds tightly to the spliceosome after the reaction and is then removed from the spliceosome, which normally requires Prp16 and ATP hydrolysis, to allow the occurrence of the second reaction. 28057857
2016-07-30 11:12:00 At the catalytic stage of splicing, suboptimal splice sites are repressed by the DEAH-box ATPases Prp16 and Prp22. study shows that these ATPases function further by enabling the spliceosome to search for and utilize alternative branch sites and 3' splice sites. 26919433
2014-09-06 11:28:00 Results indicate that the prp16-302 mutation in Prp16 stabilizes Cwc2 interactions with U6 snRNA and destabilizes Cwc2 interactions with pre-mRNA, indicating antagonistic functions of Cwc2 and Prp16. 24848011
2013-06-01 12:35:00 In the absence of the C domain, Yju2-N domain is not stably associated with the spliceosome after lariat formation, and thus bypasses the need for Prp16. 23438600
2013-03-09 10:25:00 NTR complex catalyzes the disassembly of affinity-purified spliceosomes arrested specifically after the ATP-dependent action of DEAH-box Prp2, Prp16, or Prp22 but not at steps before the action of these ATPases or upon their binding to the spliceosome. 23166295

名称对应

Type IDs
Synonymous PRP23, RNA16
Gene
UniProtKB-ID: PRP16_YEAST
UniprotKB: P15938
UniParc: UPI0000132144
EMBL: Z28311, Z27116, M31524, BK006944
EnsemblGenome: YKR086W
KO: sce:YKR086W
Nucleutide sequences
EMBL-CDS: DAA09236.1, AAA34911.1, CAA81637.1, CAA82165.1
Gene_ORFName: YKR406
EnsemblGenome_TRS: YKR086W_mRNA
Protein sequencees
EnsemblGenome_PRO: YKR086W
RefSeq: NP_013012.3
Others
UniRef100: UniRef100_P15938
UniRef90: UniRef90_P15938
UniRef50: UniRef50_P15938

全选

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