| Type | Description |
|---|---|
| Definition | phosphopantothenoylcysteine decarboxylase complex subunit SIS2 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-16 12:10:00 | Site-directed mutagenesis results indicate mutation of ScHal3 L403 has no effect on trimerization and phosphopantothenoyl-cysteine decarboxylase function. ScHal3 L405E fails to form homotrimers, but retains the capacity to bind Cab3. Remarkably, the L405E mutation decreases Hal3's ability to interact with and to inhibit Ppz1, confirming the importance of the oligomer/monomer equilibrium in Hal3's Ppz1 regulating function. | 30279472 |
| 2012-04-14 10:29:00 | The Hal3 N-terminal domain is not functional by itself, although in vitro experiments indicate that when this domain is combined with the core it has a relevant function in Hal3's heteromeric phosphopantothenoylcysteine decarboxylase activity. | 22124281 |
| 2011-02-26 10:31:00 | The aim of this work was to study mechanisms which relate the activity of Ppz1p/Hal3p complex to nonsense suppression efficiency. | 21290823 |
| 2010-01-21 00:00:00 | Results demonstrate the participation of the Hal3-Ppz1 protein complex in regulation of read-through efficiency and manifestation of non-Mendelian anti-suppressor determinant [ISP(+)]. | 17397392 |
| 2010-01-21 00:00:00 | the Ppz1-Hal3 interaction is a sensor of intracellular pH that modulates H+ and K+ homeostasis through the regulation of Trk1p activity | 16166647 |
| Type | IDs |
|---|---|
| Synonymous | HAL3 |
| Gene |
UniProtKB-ID:
SIS2_YEAST
UniprotKB:
P36024
UniParc:
UPI00001359B5
EMBL:
BK006944,
Z28297,
U01878
EnsemblGenome:
YKR072C
KO:
sce:YKR072C
|
| Nucleutide sequences |
EMBL-CDS:
DAA09223.1,
CAA82151.1,
AAA80000.1
EnsemblGenome_TRS:
YKR072C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YKR072C
RefSeq:
NP_012998.1
|
| Others |
UniRef100:
UniRef100_P36024
UniRef90:
UniRef90_P36024
UniRef50:
UniRef50_P36024
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员