| Type | Description |
|---|---|
| Definition | translation initiation factor eIF4A |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:30:00 | Distinct interactions of eIF4A and eIF4E with RNA helicase Ded1 stimulate translation in vivo. | 32469309 |
| 2019-12-07 12:14:00 | RNA substrates affect eIF4A activities by modulating the kinetic partitioning of eIF4A between futile, unproductive, and productive cycles | 30997503 |
| 2018-03-24 11:34:00 | The results from this study identify protein complexes and pathways that will make ideal targets for combination therapies with eIF4A inhibitors. | 29397069 |
| 2018-01-27 11:43:00 | These findings reveal an eIF4A-independent role for eIF4B in addition to its function as eIF4A cofactor in promoting PIC attachment or scanning on structured mRNAs. | 27601676 |
| 2017-11-04 11:12:00 | These results reveal and characterize an unexpected interdependence between the two RNA helicases and eIF4G, and suggest that Ded1p is an integral part of eIF4F, the complex comprising eIF4G, eIF4A, and eIF4E. | 27494274 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
IF4A_YEAST
UniprotKB:
P10081
UniParc:
UPI000004F92D
EMBL:
BK006943,
BK006944,
X12813,
X58099,
X12814,
Z49413,
Z28284,
U25436,
X87371
EnsemblGenome:
YKR059W,
YJL138C
KO:
sce:YJL138C,
sce:YKR059W
|
| Nucleutide sequences |
EMBL-CDS:
CAA41110.1,
CAA60817.1,
DAA09210.1,
CAA31301.1,
DAA08662.1,
AAA91645.1,
CAA31302.1,
CAA89433.1,
CAA82138.1
Gene_ORFName:
J0660
EnsemblGenome_TRS:
YJL138C_mRNA,
YKR059W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YKR059W,
YJL138C
RefSeq:
NP_012985.3
|
| Others |
UniRef100:
UniRef100_A6ZQJ1
UniRef90:
UniRef90_A6ZQJ1
UniRef50:
UniRef50_A6ZQJ1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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Ensembl: {{protein.nucleotideEnsembl}} |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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