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853880 TOF2

853880

TOF2

Tof2p

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition Tof2p

研究结论

Date Results Publications
2020-06-06 13:19:00 The authors show that Siz2 is enriched at the replication fork barrier (RFB) in the ribosomal DNA (rDNA) and also controls the homeostasis of Tof2 protein. siz2Delta resulted in increased accumulation of total Tof2 in the cell and a consequent increase in the enrichment of Tof2 at the rDNA. 31776241
2017-09-02 11:01:00 Ctf4-dependent recruitment of Dna2/Tof2 couples other processes to DNA synthesis, including rDNA copy-number regulation. 27397685
2010-01-21 00:00:00 collaborates with Cdc14 specifically in rDNA segregation, presumably by targeting Cdc14 phosphatase activity to the nucleolus during anaphase to support resolution and compaction of this repetitive and highly transcribed DNA locus 18595708
2010-01-21 00:00:00 These data support a model whereby Tof2 coordinates the biphasic release of Cdc14 during anaphase by restraining a population of Cdc14 in the nucleolus after activation of the Cdc14 early anaphase release (FEAR) network, for subsequent release by the MEN. 18923139

名称对应

Type IDs
Gene
UniProtKB-ID: TOF2_YEAST
UniprotKB: Q02208
UniParc: UPI000013B777
EMBL: Z28235, BK006944, X65124
EnsemblGenome: YKR010C
KO: sce:YKR010C
Nucleutide sequences
EMBL-CDS: CAA82080.1, CAA46242.1, DAA09166.1
Gene_ORFName: YK109
EnsemblGenome_TRS: YKR010C_mRNA
Protein sequencees
EnsemblGenome_PRO: YKR010C
RefSeq: NP_012935.3
Others
UniRef100: UniRef100_Q02208
UniRef90: UniRef90_Q02208
UniRef50: UniRef50_Q02208

全选

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研究热度

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