| Type | Description |
|---|---|
| Definition | DNA damage-responsive RNA polymerase-degradation factor DEF1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 11:40:00 | The Def1 is a novel factor for ubiquitin-dependent degradation of excess Nop1. | 31506176 |
| 2019-01-26 12:13:00 | Def1 does not play a critical role in damage-induced mutagenesis | 30172224 |
| 2018-07-07 12:10:00 | Def1 binds TFIIH and initiates RNA polymerase II transcription. | 29180430 |
| 2017-08-12 11:36:00 | Def1, known to promote ubiquitination and degradation of stalled RNA polymerase complex, also directs NER to AP lesions on the transcribed strand of an actively transcribed gene but that its function is dependent on metabolic state of the yeast cells. | 28521214 |
| 2014-08-23 11:54:00 | TLS polymerase REV1 carries out DNA lesion bypass only after the Def1-assisted removal of Pol3 from the stalled replication fork. | 24465179 |
| Type | IDs |
|---|---|
| Synonymous | VID31 |
| Gene |
UniProtKB-ID:
DEF1_YEAST
UniprotKB:
P35732
UniParc:
UPI000004F934
EMBL:
X75781,
Z28054,
BK006944
EnsemblGenome:
YKL054C
KO:
sce:YKL054C
|
| Nucleutide sequences |
EMBL-CDS:
CAA53418.1,
CAA81890.1,
DAA09103.1
Gene_ORFName:
YKL308
EnsemblGenome_TRS:
YKL054C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YKL054C
RefSeq:
NP_012869.1
|
| Others |
UniRef100:
UniRef100_P35732
UniRef90:
UniRef90_P35732
UniRef50:
UniRef50_P35732
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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