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853681 SNU114

853681

SNU114

U5 snRNP GTPase SNU114

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition U5 snRNP GTPase SNU114

研究结论

Date Results Publications
2020-08-01 14:08:00 Results suggest that the Snu114-GTP-Prp8 module serves as a relay station during spliceosome activation and disassembly, but that GTPase activity may be dispensable for splicing. 32196113
2014-05-10 10:12:00 We propose that the U5 snRNA IL1 is a platform for protein binding and is required for , Brr2 and Snu114 association with the U5 snRNA to form the U5 snRNP. 23857713
2010-02-15 11:54:00 Data suggest that the RNA base pairing state is directly or indirectly sensed by the Snu114p G domain. 19620389
2010-01-21 00:00:00 GTP hydrolysis results in a rearrangement between Prp8 and the C terminus of Snu114 that leads to release of U1 and U4, thus activating the spliceosome for catalysis. 15911574
2010-01-21 00:00:00 Snu114p serves as a signal-dependent switch that transduces signals to Brr2p to control spliceosome dynamics. 16885028

名称对应

Type IDs
Synonymous GIN10
Gene
UniProtKB-ID: SN114_YEAST
UniprotKB: P36048
UniParc: UPI00000530DE
EMBL: BK006944, Z26878, Z28173, D28149
EnsemblGenome: YKL173W
KO: sce:YKL173W
Nucleutide sequences
EMBL-CDS: BAA05682.1, DAA08993.1, CAA82015.1, CAA81514.1
Gene_ORFName: YKL637
EnsemblGenome_TRS: YKL173W_mRNA
Protein sequencees
EnsemblGenome_PRO: YKL173W
RefSeq: NP_012748.1
Others
UniRef100: UniRef100_P36048
UniRef90: UniRef90_P36048
UniRef50: UniRef50_P36048

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研究热度

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