| Type | Description |
|---|---|
| Definition | phosphatidylinositol-3-phosphatase SAC1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:32:00 | Co-opted Cellular Sac1 Lipid Phosphatase and PI(4)P Phosphoinositide Are Key Host Factors during the Biogenesis of the Tombusvirus Replication Compartment. | 32269127 |
| 2019-12-14 12:00:00 | The increase in Golgi PtdIns(4)P due to Sac1 inactivation, however, is faster than that due to Sac1 translocation. Exposure of cells to H2O2 also increased membrane protein trafficking from the Golgi to the plasma membrane as well as protein secretion. | 30448513 |
| 2019-07-20 12:57:00 | The authors report that acute inhibition of SAC1 causes accumulation of phosphatidylinositol 4-phosphate in the endoplasmic reticulum, that SAC1 does not enrich at membrane contact sites, and that SAC1 has little activity in 'trans', unless a linker is added between its endoplasmic reticulum-anchored and catalytic domains. | 29461204 |
| 2015-08-22 10:19:00 | this study showed that the PI4P-phosphatase Sac1p, by maintaining a PI4P gradient at the endoplasmic reticulum / plasma membrane interface, drove phosphatidylserine transport. | 26206936 |
| 2014-11-22 10:57:00 | Disruption of the Sac1-Vps74 interface results in a broader distribution of phosphatidylinositol 4-phosphate within the Golgi apparatus and failure to maintain residence of a medial Golgi mannosyltransferase. | 25113029 |
| Type | IDs |
|---|---|
| Synonymous | RSD1 |
| Gene |
UniProtKB-ID:
SAC1_YEAST
UniprotKB:
P32368
UniParc:
UPI00001351E8
EMBL:
Z28212,
X51672,
U39947,
BK006944,
X75951
EnsemblGenome:
YKL212W
KO:
sce:YKL212W
|
| Nucleutide sequences |
EMBL-CDS:
CAA82057.1,
CAA53561.1,
AAA82257.1,
CAA35979.1,
DAA08957.1
EnsemblGenome_TRS:
YKL212W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YKL212W
RefSeq:
NP_012710.1
|
| Others |
UniRef100:
UniRef100_P32368
UniRef90:
UniRef90_P32368
UniRef50:
UniRef50_P32368
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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