| Type | Description |
|---|---|
| Definition | myosin light chain kinase 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:55:00 | FLNC and MYLK2 Gene Mutations in a Chinese Family with Different Phenotypes of Cardiomyopathy. | 33455984 |
| 2017-03-18 10:35:00 | Chinese family with dual LQT1 and HCM phenotypes associated with tetrad heterozygous mutations in KCNQ1, MYH7, MYLK2, and TMEM70 mutations. | 25825456 |
| 2010-01-21 00:00:00 | Data show that that the prototypical CaM target sequence skMLCK, a fragment from skeletal muscle myosin light chain kinase, binds to CaM in a highly cooperative way, while only a lower degree of interdomain binding cooperativity emerges for CaMKK. | 19667195 |
| 2010-01-21 00:00:00 | These data suggest that the kinase domain of MYLK2 is rarely mutated in common human carcinomas and that it does not play a dominant role in cancer pathogenesis. | 16448786 |
| 2010-01-21 00:00:00 | MYLK gene is a risk factor for the development of acute lung injuries. | 18828194 |
| Type | IDs |
|---|---|
| Synonymous | KMLC, MLCK, MLCK2, skMLCK |
| Gene |
UniProtKB-ID:
MYLK2_HUMAN
UniprotKB:
Q9H1R3
UniParc:
UPI0000041851
EMBL:
AF325549,
AL160175,
BC007753,
AJ272502,
BC092413,
BC069627,
BC127622
Ensembl:
ENSG00000101306
KO:
hsa:85366
|
| Nucleutide sequences |
EMBL-CDS:
AAK15494.1,
AAI27623.1,
AAH07753.1,
AAH69627.1,
CAC81354.1,
AAH92413.1
Ensembl_TRS:
ENST00000375994,
ENST00000375985
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000365152,
ENSP00000365162
RefSeq:
NP_149109.1
|
| Others |
UniRef100:
UniRef100_Q9H1R3
UniRef90:
UniRef90_Q9H1R3
UniRef50:
UniRef50_Q9H1R3
UniGene:
Hs.86092
CCDS:
CCDS13191.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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