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853583 JHD2

853583

JHD2

histone demethylase

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition histone demethylase

研究结论

Date Results Publications
2018-08-25 10:03:00 A model has been proposed wherein combined actions of Set1 and Jhd2 via modulating H3K4 methylation-demethylation together control chromatin dynamics during various facets of transcriptional regulation. 27325136
2016-03-19 10:45:00 H2B Lys-123 ubiquitination blocks Jhd2 from accessing its binding site on chromatin, and thereby, we have uncovered a second mechanism by which H2B ubiquitination contributes to the trans-histone regulation of H3K4 methylation. 26451043
2015-05-23 11:49:00 Jhd2, an evolutionarily conserved JARID1 family H3 Lys4 demethylase, effects all states of methylated histone H3K4 within the NTS regions of rDNA, and its activity is required for the regulation of rDNA silencing in a Sir2-independent manner. 25248920
2010-09-27 11:29:00 the JmjN domain of Jhd2 is important for its protein stability, and the plant homeodomain (PHD) finger mediates its chromatin association independent of H3K4 methylation 20538609
2010-01-21 00:00:00 A novel budding yeast JmjC domain-containing H3-K4 demethylase, Jhd2p, that antagonizes the trimethyl modification state and contributes to regulation of telomeric silencing. 17310254

名称对应

Type IDs
Synonymous KDM5
Gene
UniProtKB-ID: JHD2_YEAST
UniprotKB: P47156
UniParc: UPI000013B4ED
EMBL: Z49620, Z49619, BK006943
EnsemblGenome: YJR119C
KO: sce:YJR119C
Nucleutide sequences
EMBL-CDS: DAA08904.1, CAA89649.1, CAA89651.1
Gene_ORFName: J2035
EnsemblGenome_TRS: YJR119C_mRNA
Protein sequencees
EnsemblGenome_PRO: YJR119C
RefSeq: NP_012653.1
Others
UniRef100: UniRef100_P47156
UniRef90: UniRef90_P47156
UniRef50: UniRef50_P47156

全选

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研究热度

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