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853562 YUH1

853562

YUH1

ubiquitin-specific protease YUH1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition ubiquitin-specific protease YUH1

研究结论

Date Results Publications
2019-04-06 11:51:00 Following mutagenesis and yeast display screening, this study identified a variant of the yeast ubiquitin C-terminal hydrolase Yuh1 that has a 28-fold improvement in the transamidation to hydrolysis ratio relative to the wild type enzyme. The switch in activity enables robust autoubiquitination of a lysine in the crossover loop to form an isopeptide bond. 30137960
2010-01-21 00:00:00 Data show that upon complexation of ubiquitin with YUH1, 13C NMR paramagnetic shifts associated with the protein binding interface were reduced by 0.05 ppm or more. 19520148

名称对应

Type IDs
Gene
UniProtKB-ID: UBL1_YEAST
UniprotKB: P35127
UniParc: UPI00001379CD
EMBL: Z49599, BK006943
EnsemblGenome: YJR099W
KO: sce:YJR099W
Nucleutide sequences
EMBL-CDS: DAA08884.1, CAA89629.1
Gene_ORFName: J1941
EnsemblGenome_TRS: YJR099W_mRNA
Protein sequencees
EnsemblGenome_PRO: YJR099W
RefSeq: NP_012633.1
Others
UniRef100: UniRef100_P35127
UniRef90: UniRef90_P35127
UniRef50: UniRef50_P35127

全选

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研究热度

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