| Type | Description |
|---|---|
| Definition | actin-related protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-05-05 11:38:00 | These studies provide evidence that WASP (Las17) and WIP (Vrp1) play central roles in establishment of a robust multivalent Src homology 3 domain-proline-rich motif network in vivo, giving Actin-related protein 2/3 complex assembly onset at endocytic sites a switch-like behavior. | 28813247 |
| 2017-08-12 11:45:00 | WASP displaces the autoinhibitory Arp3 C-terminal tail from a hydrophobic groove at Arp3's barbed end to destabilize the inactive state, providing a mechanism by which WASP stimulates the short-pitch conformation and activates the Arp2/3 complex. | 27325766 |
| 2017-07-15 10:27:00 | Studies indicate that the WASP homologue Las17 is able to nucleate actin independently of Arp2/3 through the function of G-actin-binding activities in its polyproline region. | 27911716 |
| 2013-05-18 10:15:00 | data does not support the simple hypothesis that the primary role for Arp2/3 regulators is to recruit and activate Arp2/3; rather data suggests that these regulators may be playing more subtle roles in establishing functional networks in vivo | 23200048 |
| 2011-07-16 11:30:00 | development of a direct tethering recruitment model for activation of Arp2/3 complex by Crn1 | 21454476 |
| Type | IDs |
|---|---|
| Synonymous | ACT4 |
| Gene |
UniProtKB-ID:
ARP3_YEAST
UniprotKB:
P47117
UniParc:
UPI00000531DC
EMBL:
BK006943,
Z49565,
L47993,
L37111
EnsemblGenome:
YJR065C
KO:
sce:YJR065C
|
| Nucleutide sequences |
EMBL-CDS:
AAB39291.1,
AAC37503.1,
DAA08852.1,
CAA89593.1
Gene_ORFName:
J1760
EnsemblGenome_TRS:
YJR065C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YJR065C
RefSeq:
NP_012599.3
|
| Others |
UniRef100:
UniRef100_P47117
UniRef90:
UniRef90_P47117
UniRef50:
UniRef50_P32390
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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