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853500 POL32

853500

POL32

DNA polymerase delta subunit POL32

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition DNA polymerase delta subunit POL32

研究结论

Date Results Publications
2020-12-19 13:43:00 Structure and mechanism of B-family DNA polymerase zeta specialized for translesion DNA synthesis. 32807989
2020-02-15 13:26:00 The structure reveals an unexpected arrangement in which the regulatory subunits (Pol31 and Pol32) lie next to the exonuclease domain of Pol3 but do not engage the DNA. 31582849
2019-08-31 12:32:00 PCNA enhanced the nucleotide incorporation rate by >10 fold. Compared to wild-type, a growth-defective yeast PCNA mutant (DD41,42AA) showed substantially less stimulation of the Pol delta nucleotide incorporation rate, identifying the face of PCNA that is important for the acceleration of catalysis. 30605530
2019-07-20 12:29:00 we observed a similar increase in repeat instability in RNase H-deficient cells when we either changed the direction of transcription-replication collisions, or flipped the repeat sequence such that the (UUC)n run occurred in the transcript. The increase in repeat expansions in RNase H-deficient strains was dependent on Rad52 and Pol32 proteins, suggesting that break-induced replication (BIR) is responsible for this effe 29447396
2015-10-24 11:22:00 Rev3 role in Pol32 regulation in the course of mutagenesis 24819597

名称对应

Type IDs
Synonymous REV5
Gene
UniProtKB-ID: DPOD3_YEAST
UniprotKB: P47110
UniParc: UPI0000129740
EMBL: BK006943, Z49543, AY557918, L36344
EnsemblGenome: YJR043C
KO: sce:YJR043C
Nucleutide sequences
EMBL-CDS: AAS56244.1, AAA88745.1, DAA08830.1, CAA89571.1
Gene_ORFName: J1626
EnsemblGenome_TRS: YJR043C_mRNA
Protein sequencees
EnsemblGenome_PRO: YJR043C
RefSeq: NP_012577.1
Others
UniRef100: UniRef100_P47110
UniRef90: UniRef90_P47110
UniRef50: UniRef50_P47110

全选

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研究热度

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