| Type | Description |
|---|---|
| Definition | chromobox 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:24:00 | Circular RNA hsa_circ_0008039 promotes proliferation, migration and invasion of breast cancer cells through upregulating CBX4 via sponging miR-515-5p. | 32141558 |
| 2021-02-27 13:47:00 | SUMO E3 ligase CBX4 regulates hTERT-mediated transcription of CDH1 and promotes breast cancer cell migration and invasion. | 32926159 |
| 2020-05-30 13:45:00 | Chromobox homolog 4 (CBX4) is overexpressed in osteosarcoma cell lines and tissues. CBX4 promotes metastasis by transcriptionally up-regulating Runx2 via the recruitment of GCN5 to the Runx2 promoter. The phosphorylation of CBX4 at T437 by casein kinase 1alpha (CK1alpha) facilitates its ubiquitination at both K178 and K280 and subsequent degradation by CHIP, and this phosphorylation of CBX4 could be reduced by TNFalpha. | 32111827 |
| 2020-05-23 13:20:00 | role of CBX4 in maintaining cellular homeostasis in mesenchymal stem cells | 30917318 |
| 2020-03-07 10:25:00 | This is the evidence supporting the interaction between GRM4 and CBX4, which could inhibit the malignant behavior of osteosarcoma cells through the GRM4/CBX4/HIF-1alpha signaling pathway | 31581881 |
| Type | IDs |
|---|---|
| Synonymous | NBP16, PC2 |
| Gene |
UniProtKB-ID:
CBX4_HUMAN,
A0A0S2Z5B2_HUMAN
UniprotKB:
O00257,
A0A0S2Z5B2
UniParc:
UPI000013D82E,
UPI0000169F5D
EMBL:
AC100791,
AF013956,
AY390430,
EU439707,
BC014967,
U94344,
KU178423,
CH471099
Ensembl:
ENSG00000141582
KO:
hsa:8535
|
| Nucleutide sequences |
EMBL-CDS:
AAB80718.1,
AAQ97596.1,
AAH14967.1,
ACA49234.1,
AAB62734.1,
EAW89572.1,
ALQ33881.1
Gene_ORFName:
hCG_28566
Ensembl_TRS:
ENST00000269397
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000269397
RefSeq:
NP_003646.2,
XP_011523701.1
|
| Others |
UniRef100:
UniRef100_O00257
UniRef90:
UniRef90_O00257
UniRef50:
UniRef50_O00257
UniGene:
Hs.405046
CCDS:
CCDS32758.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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