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853492 RAD26

853492

RAD26

DNA-dependent ATPase RAD26

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition DNA-dependent ATPase RAD26

研究结论

Date Results Publications
2020-09-26 13:09:00 Genome-wide role of Rad26 in promoting transcription-coupled nucleotide excision repair in yeast chromatin. 32690696
2020-03-28 11:26:00 Transcriptional nucleotide misincorporation is not implicated in TC-NER, and moderate eviction of Spt5 and promotion of error-free transcriptional bypass of DNA lesions by Rad26 facilitates TC-NER. 30790631
2018-04-14 11:51:00 structure of the S. cerevisiae Pol II-Rad26 complex solved by cryo-electron microscopy; structure reveals that Rad26 binds to the DNA upstream of Pol II, where it markedly alters its path; structural and functional data suggest that the conserved Swi2/Snf2-family core ATPase domain promotes the forward movement of Pol II, and elucidate key roles for Rad26 in both TCR and transcription elongation 29168508
2016-08-20 12:06:00 Rad26 may facilitate transcription coupled nucleotide excision repair (TC-NER) indirectly, by antagonizing the action of TC-NER repressors that normally promote transcription elongation. 26429063
2014-04-26 10:43:00 Data indicate that RAD26 deletion does not reduce expression of nucleotide excision repair (NER) factors but affects RPB2 transcription during NER. 23991048

名称对应

Type IDs
Gene
UniProtKB-ID: RAD26_YEAST
UniprotKB: P40352
UniParc: UPI0000133021
EMBL: L26910, Z49535, BK006943, X81635
EnsemblGenome: YJR035W
KO: sce:YJR035W
Nucleutide sequences
EMBL-CDS: AAA34655.1, DAA08824.1, CAA57290.1, CAA89562.1
Gene_ORFName: J1606
EnsemblGenome_TRS: YJR035W_mRNA
Protein sequencees
EnsemblGenome_PRO: YJR035W
RefSeq: NP_012569.1
Others
UniRef100: UniRef100_P40352
UniRef90: UniRef90_P40352
UniRef50: UniRef50_P40352

全选

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研究热度

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