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853439 MAD3

853439

MAD3

Mad3p

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition Mad3p

研究结论

Date Results Publications
2020-12-05 13:04:00 The Phosphatase PP1 Promotes Mitotic Slippage through Mad3 Dephosphorylation. 31928870
2020-07-11 10:58:00 The Bub1 TPR domain is both necessary and sufficient to bind and recruit Mad3. 31257143
2013-05-04 11:34:00 our results are consistent with a role of Mad3 as the main interactor of Mad2 via the dimerization surface. Mad3 being required to stabilize the Cdc20:C-Mad2 complex implies that the complex by itself is unstable. 23000150
2012-08-11 11:27:00 Mad3 is required for the stable binding of Mad2 to Cdc20 in vivo, which is sufficient to inhibit APC activity and is the most downstream event in spindle checkpoint activation. 22209528
2010-05-03 11:25:00 data suggest important roles of ubiquitination in mediating IGF-1R signaling and degradation 17406666

名称对应

Type IDs
Gene
UniProtKB-ID: MAD3_YEAST
UniprotKB: P47074
UniParc: UPI000012EB19
EMBL: Z49288, BK006943
EnsemblGenome: YJL013C
KO: sce:YJL013C
Nucleutide sequences
EMBL-CDS: DAA08780.1, CAA89304.1
Gene_ORFName: J1341
EnsemblGenome_TRS: YJL013C_mRNA
Protein sequencees
EnsemblGenome_PRO: YJL013C
RefSeq: NP_012521.3
Others
UniRef100: UniRef100_P47074
UniRef90: UniRef90_P47074
UniRef50: UniRef50_P47074

全选

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研究热度

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