| Type | Description |
|---|---|
| Definition | ATP-dependent RNA helicase MTR4 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:51:00 | Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome. | 33326748 |
| 2018-05-05 11:56:00 | Mpp6-exosomes can recruit Mtr4, while Mpp6 and Rrp47 each contribute to Mtr4-dependent RNA decay, with maximal Mtr4-dependent decay observed with both cofactors. | 28742025 |
| 2017-12-09 13:13:00 | report the 3.2 A resolution crystal structure of S. cerevisiae Mtr4 bound to the interacting region of Nop53, revealing how the KOW domain of the helicase recognizes the AIM sequence of Nop53 with a network of hydrophobic and electrostatic interactions | 28883156 |
| 2017-04-29 12:35:00 | Rrp41 mutations blocked substrate passage through the channel to Rrp44 only for cytoplasmic mRNAs, supporting the predicted widening of the lumen in the Rrp6-associated.Many exosome substrates exhibited clear preferences for a specific path to Rrp44. Both threading and direct access routes involve the RNA helicase Mtr4 | 28355211 |
| 2016-07-30 11:59:00 | Mtr4p structural domain mutants in the helicase core reduced Mtr4p RNA binding, ATPase activity and unwinding activity in vitro. | 26820724 |
| Type | IDs |
|---|---|
| Synonymous | DOB1 |
| Gene |
UniProtKB-ID:
MTR4_YEAST
UniprotKB:
P47047
UniParc:
UPI0000052EB1
EMBL:
BK006943,
Z49325
EnsemblGenome:
YJL050W
KO:
sce:YJL050W
|
| Nucleutide sequences |
EMBL-CDS:
CAA89341.1,
DAA08749.1
Gene_ORFName:
J1158
EnsemblGenome_TRS:
YJL050W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YJL050W
RefSeq:
NP_012485.1
|
| Others |
UniRef100:
UniRef100_P47047
UniRef90:
UniRef90_P47047
UniRef50:
UniRef50_P47047
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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