| Type | Description |
|---|---|
| Definition | cohesin subunit SMC3 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 11:00:00 | ATP-binding and Smc1-Smc3 heterodimerization promote conformational changes within the ATPase that are transmitted to the Smc coiled-coil domains. | 32066964 |
| 2020-02-22 12:34:00 | The authors show here that Scc2 also actively maintains cohesin on chromosomes during G1 in S. cerevisiae cells. It does so by blocking a Wapl-independent release reaction that requires opening the cohesin ring at its Smc3/Scc1 interface as well as the D loop of Smc1's ATPase. | 31225797 |
| 2018-11-10 11:56:00 | The X. laevis Eco2 bound to its primary and secondary Smc3 substrates demonstrate the plasticity of the substrate-binding site, which confers substrate specificity by concerted conformational changes of the central beta-hairpin and the C-terminal extension. | 28290497 |
| 2017-11-25 12:38:00 | Smc3 deacetylation by Hos1, triggered by Scc1 cleavage, facilitates efficient dissolution of sister chromatid cohesion during early metaphase. | 29100057 |
| 2017-09-09 11:31:00 | A reversible association between Smc1 and Smc3 coiled coils is regulated by lysine acetylation and is required for cohesin association with the DNA. | 27618487 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SMC3_YEAST
UniprotKB:
P47037
UniParc:
UPI0000052FAC
EMBL:
X88851,
BK006943,
Z49349,
Y14278
EnsemblGenome:
YJL074C
KO:
sce:YJL074C
|
| Nucleutide sequences |
EMBL-CDS:
DAA08725.1,
CAA61313.1,
CAA74655.1,
CAA89366.1
Gene_ORFName:
J1049
EnsemblGenome_TRS:
YJL074C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YJL074C
RefSeq:
NP_012461.1
|
| Others |
UniRef100:
UniRef100_P47037
UniRef90:
UniRef90_P47037
UniRef50:
UniRef50_P47037
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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