| Type | Description |
|---|---|
| Definition | protein kinase activating protein DPB11 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-13 11:38:00 | The Dpb11 obtained by endogenous purification strongly stimulates the Mec1 kinase activity and promotes the changes in conformational distribution. This observation suggests the Dpb11 activates Mec1 kinase probably through modulation in the kinase conformations. | 31349966 |
| 2018-01-13 12:18:00 | Budding yeast Fun30 and human SMARCAD1 are cell cycle-regulated by interaction with the DNA double strand break-localized scaffold protein Dpb11/TOPBP1, respectively. In yeast, this protein assembly additionally comprises the 9-1-1 damage sensor, is involved in localizing Fun30 to damaged chromatin, and thus is required for efficient long-range resection of DNA double strand breaks. | 28063255 |
| 2015-12-05 11:40:00 | The Slx4-Dpb11 scaffold complex coordinates the response to replication fork stalling in S-phase and the subsequent mitosis. | 25496009 |
| 2015-07-04 13:42:00 | Upon extrusion of ssDNA from the central channel of Mcm2-7, Dpb11 dissociates from Mcm2-7, and Dpb11 binds to ssDNA, thereby allowing GINS to bind to Cdc45.Mcm2-7 | 25659432 |
| 2014-12-20 12:52:00 | The ddc2-S4 mutation decreases phosphorylation of histone H2A more significantly than the absence of Ddc1 and Dpb11 function does. | 24586187 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
DPB11_YEAST
UniprotKB:
P47027
UniParc:
UPI000013B5C1
EMBL:
D42168,
X83502,
BK006943,
Z49365
EnsemblGenome:
YJL090C
KO:
sce:YJL090C
|
| Nucleutide sequences |
EMBL-CDS:
CAA58477.1,
CAA89383.1,
DAA08710.1,
BAA07725.2
Gene_ORFName:
J0918
EnsemblGenome_TRS:
YJL090C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YJL090C
RefSeq:
NP_012445.1
|
| Others |
UniRef100:
UniRef100_P47027
UniRef90:
UniRef90_P47027
UniRef50:
UniRef50_P47027
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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