Type | Description |
---|---|
Definition | DNA helicase SRS2 |
Date | Results | Publications |
---|---|---|
2020-01-25 10:17:00 | Srs2 C-terminal Rad51 interaction domain is essential for crossover control in S. cerevisiae. | 31142613 |
2019-07-27 12:08:00 | DNA helicase domain of Saccharomyces cerevisiae yeast Srs2 protein is needed to deal with DNA damage and assist in DNA replication during vegetative growth and in meiosis. The interactions of Srs2 with Rad51 Recombinase and proliferating cell nuclear Antigen PCNA are dispensable for the main role of Srs2. | 30018112 |
2018-09-22 11:48:00 | Two main activities of Srs2, strippase and helicase, counteract toxic joint intermediates formed during break-induced replication by preventing their formation and promoting their disruption, respectively. | 29176630 |
2018-07-28 12:19:00 | Srs2 rapidly disrupts small heteroduplex DNA joints bound to Rad51 filaments. | 29241544 |
2018-02-17 10:48:00 | These data establish a biochemical mechanism for the role of Srs2 in crossover suppression by promoting synthesis-dependent strand annealing through disruption of DNA polymerase delta-extended D-loops. | 28535142 |
Type | IDs |
---|---|
Synonymous | HPR5 |
Gene |
UniProtKB-ID:
SRS2_YEAST
UniprotKB:
P12954
UniParc:
UPI0000168360
EMBL:
X77087,
BK006943,
X15665,
Z49367
EnsemblGenome:
YJL092W
KO:
sce:YJL092W
|
Nucleutide sequences |
EMBL-CDS:
CAA89385.1,
DAA08708.1,
CAA33706.1,
CAA54361.1
Gene_ORFName:
J0913
EnsemblGenome_TRS:
YJL092W_mRNA
|
Protein sequencees |
EnsemblGenome_PRO:
YJL092W
RefSeq:
NP_012443.1
|
Others |
UniRef100:
UniRef100_P12954
UniRef90:
UniRef90_P12954
UniRef50:
UniRef50_P12954
|