| Type | Description |
|---|---|
| Definition | COP9 signalosome subunit 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-29 11:31:00 | COPS3 may be closely related to the progress of PCa. Knockdown of COPS3 inhibited the progress of PCa through reducing the levels of phosphorylated P38 MAPK and impaired the epithelial-mesenchymal transition process. | 31509289 |
| 2019-05-11 10:15:00 | these data reveal a novel function of COPS3 in the regulation of autophagy and highlight the relationship between autophagy and metastasis in osteosarcoma cells. | 29970115 |
| 2019-02-02 11:53:00 | COPS3 may be a new potential target of clear cell renal cell carcinoma. | 29477618 |
| 2018-06-23 11:04:00 | Here the authors identify a potential mechanism by which desmosomes assist the de-neddylating COP9 signalosome (CSN) in attenuating EGFR through an association between the Cops3 subunit of the CSN and desmosomal components, Desmoglein1 (Dsg1) and Desmoplakin (Dp), to promote epidermal differentiation. | 28891468 |
| 2012-06-23 10:06:00 | this study demonstrates Csn3 as an oncogene that regulates the tumorigenesis process in hepatocellular carcinoma (HCC) cells. | 22237956 |
| Type | IDs |
|---|---|
| Synonymous | CSN3, SGN3 |
| Gene |
UniProtKB-ID:
CSN3_HUMAN,
B4DN01_HUMAN
UniprotKB:
Q9UNS2,
B4DN01
UniParc:
UPI00017A7952,
UPI00001696F0,
UPI0000073FD1
EMBL:
BC001891,
AF031647,
CH471196,
AC055811,
AK312476,
AK302304,
AK316400,
AF098109,
AK297706
Ensembl:
ENSG00000141030
KO:
hsa:8533
|
| Nucleutide sequences |
EMBL-CDS:
BAG35380.1,
EAW55712.1,
BAH14771.1,
AAD41247.1,
AAH01891.1,
AAC14197.1,
BAG63643.1,
BAG60063.1
Ensembl_TRS:
ENST00000268717,
ENST00000539941
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000437606,
ENSP00000268717
RefSeq:
XP_005256897.1,
XP_005256899.1,
NP_001303286.1,
NP_001303285.1,
NP_003644.2,
NP_001303284.1,
NP_001303283.1,
NP_001186054.1,
XP_005256894.1,
XP_016880735.1,
NP_001303287.1
|
| Others |
UniRef100:
UniRef100_Q9UNS2,
UniRef100_B4DN01
UniRef90:
UniRef90_B4DN01,
UniRef90_Q9UNS2
UniRef50:
UniRef50_A0A444SDU6,
UniRef50_Q9UNS2
UniGene:
Hs.6076
CCDS:
CCDS11183.1,
CCDS56022.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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