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853252 SWE1

853252

SWE1

tyrosine protein kinase SWE1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition tyrosine protein kinase SWE1

研究结论

Date Results Publications
2020-02-15 12:59:00 Here, we show that Rts1 is required for the proportional relationship between cell size and growth rate during mitosis. Moreover, nutrients and Rts1 influence the duration and extent of growth in mitosis via Wee1 and Pds1/securin, two conserved regulators of mitotic progression. 31488515
2019-12-07 11:44:00 Swe1 and the Polo-like kinase Cdc5 control the balance between phosphorylated and unphosphorylated forms of Mih1, which is, in turn, important for mitotic spindle elongation. 30072442
2019-06-01 12:03:00 Moreover, the authors show that high levels of histones promote Swe1(WEE1) stabilisation thereby triggering the phosphorylation and inhibition of Cdc28(CDK1) through a mechanism different of the canonical DNA damage response. 29580382
2019-05-25 10:09:00 strict temporal regulation of M-phase cyclin-dependent kinase (CDK; M-CDK) is important for polarity establishment and morphogenesis. Cells with premature M-CDK activity caused by loss of checkpoint kinase Swe1 failed to polarize and underwent anaphase without budding. Mutants with increased Swe1-dependent M-CDK inhibition showed additional or more penetrant phenotypes in RTG than mitosis 29743192
2017-09-23 12:28:00 Wee1 distinguishes spindle pole bodies to guide their pattern of age-dependent segregation. 28714971

名称对应

Type IDs
Synonymous WEE1
Gene
UniProtKB-ID: SWE1_YEAST
UniprotKB: P32944
UniParc: UPI0000036C68
EMBL: X73966, Z49462, BK006943
EnsemblGenome: YJL187C
KO: sce:YJL187C
Nucleutide sequences
EMBL-CDS: CAA89482.1, DAA08619.1, CAA52150.1
Gene_ORFName: J0406
EnsemblGenome_TRS: YJL187C_mRNA
Protein sequencees
EnsemblGenome_PRO: YJL187C
RefSeq: NP_012348.1
Others
UniRef100: UniRef100_P32944
UniRef90: UniRef90_P32944
UniRef50: UniRef50_P32944

全选

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研究热度

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