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853174 RAD2

853174

RAD2

ssDNA endodeoxyribonuclease RAD2

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition ssDNA endodeoxyribonuclease RAD2

研究结论

Date Results Publications
2019-12-21 12:01:00 In a mutant affected in Pol II phosphorylation leading to Mediator stabilization on core promoters, Rad2 genome-wide occupancy shifts towards core promoters following that of Mediator, but decreases on transcribed regions together with Pol II. 31299084
2017-12-30 10:15:00 Rad2 and rad27 overexpression increases genomic instability in yeast. Rad2 and Rad27 causes DNA breaks that are processed by different repair functions. 28704715
2015-01-24 11:52:00 THe data suggest that in contrast to related enzymes (FEN1 and EXO1), the Rad2 active site may be more accessible, which would create an exit route for DNA substrates without a free 5' end. 25120270
2014-11-22 13:02:00 Study shows that Rad2p interacts with PCNA through its proliferating cell nuclear antigen-binding domain (PCNA-BD) and the PCNA-BD of Rad2p plays a role in UV-induced mutagenesis. 24674623
2012-10-06 10:21:00 Structure determination of a Rad2-Tfb1PH complex indicates that Rad2 binds to TFIIH using a similar motif as TFIIEalpha uses to bind TFIIH in the pre-initiation complex. 22373916

名称对应

Type IDs
Gene
UniProtKB-ID: RAD2_YEAST
UniprotKB: P07276
UniParc: UPI000013307B
EMBL: M10275, BK006941, AY692857, Z73043, Y07777
EnsemblGenome: YGR258C
KO: sce:YGR258C
Nucleutide sequences
EMBL-CDS: AAA66928.1, CAA69080.1, CAA97287.1, AAT92876.1, DAA08349.1
EnsemblGenome_TRS: YGR258C_mRNA
Protein sequencees
EnsemblGenome_PRO: YGR258C
RefSeq: NP_011774.1
Others
UniRef100: UniRef100_P07276
UniRef90: UniRef90_P07276
UniRef50: UniRef50_P07276

全选

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研究热度

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