| Type | Description |
|---|---|
| Definition | histone acetyltransferase GCN5 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 13:57:00 | Gcn5 and Rpd3 have a limited role in the regulation of cell cycle transcripts during the G1 and S phases in Saccharomyces cerevisiae. | 31337860 |
| 2020-06-27 10:40:00 | The Gcn5-Ada2-Ada3 (ADA) histone acetyltransferase complexes have the capacity to crotonylate histones and crotonylate lysines in the N-terminal tails of histone H3 and H4. Crotonylation selectively affects gene transcription in vivo in a manner dependent on Gcn5 and Esa1. | 31699900 |
| 2019-10-19 12:12:00 | work argues that nonhistone protein acetylation by Gcn5 is determined in part by specific amino acids surrounding target lysines but that even optimal sequences require both Ada2 and Ada3 for robust acetylation. | 30804216 |
| 2018-10-20 11:19:00 | the Ada2 SANT domain does not activate Gcn5's activity by directly affecting histone peptide binding as previously proposed. Instead, the Ada2 SANT domain enhances Gcn5 binding of the enzymatic cosubstrate acetyl-CoA. | 30224453 |
| 2018-01-06 11:17:00 | This replication-guided H3K9ac was fully dependent on the acetyltransferase Rtt109, while expression-guided H3K9ac was deposited by Gcn5. Further, topoisomerase depletion intensified H3K9ac in front of the replication fork and in sites where RNA polymerase II was trapped, suggesting supercoiling stresses trigger H3K9 acetylation. | 27225843 |
| Type | IDs |
|---|---|
| Synonymous | AAS104, ADA4, KAT2, SWI9 |
| Gene |
UniProtKB-ID:
GCN5_YEAST
UniprotKB:
Q03330
UniParc:
UPI0000053126
EMBL:
AY693215,
Z73037,
X99228,
BK006941,
X68628
EnsemblGenome:
YGR252W
KO:
sce:YGR252W
|
| Nucleutide sequences |
EMBL-CDS:
AAT93234.1,
DAA08343.1,
CAA97281.1,
CAA67614.1,
CAA48602.1
EnsemblGenome_TRS:
YGR252W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YGR252W
RefSeq:
NP_011768.1
|
| Others |
UniRef100:
UniRef100_Q03330
UniRef90:
UniRef90_Q03330
UniRef50:
UniRef50_Q03330
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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