| Type | Description |
|---|---|
| Definition | ubiquitin-binding ESCRT-I subunit protein MVB12 |
| Date | Results | Publications |
|---|---|---|
| 2010-01-21 00:00:00 | Mvb12 stabilizes ESCRT-I in an oligomeric, inactive state in the cytosol to ensure that the ordered recruitment and assembly of ESCRT-I and -II is spatially and temporally restricted to the surface of the endosome after activation of the MVB reaction. | 17145965 |
| 2010-01-21 00:00:00 | These data support a model in which Mvb12 impacts the selection of multivesicular body cargoes by modulating the cargo recognition capabilities of ESCRT-I. | 17151358 |
| 2010-01-21 00:00:00 | Mvb12 may function in regulating the interactions of ESCRT-I with cargo and other proteins of the ESCRT machinery to efficiently coordinate cargo sorting and release of ESCRT-I from the multivesicular body vesicles. | 17135292 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
MVB12_YEAST
UniprotKB:
P42939
UniParc:
UPI000013AFA1
EMBL:
Z49133,
AY692570,
Z72991,
BK006941
EnsemblGenome:
YGR206W
KO:
sce:YGR206W
|
| Nucleutide sequences |
EMBL-CDS:
AAT92589.1,
CAA88999.1,
CAA97233.1,
DAA08300.1
Gene_ORFName:
G7740
EnsemblGenome_TRS:
YGR206W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YGR206W
RefSeq:
NP_011722.3
|
| Others |
UniRef100:
UniRef100_P42939
UniRef90:
UniRef90_P42939
UniRef50:
UniRef50_P42939
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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