| Type | Description |
|---|---|
| Definition | Pbp1p |
| Date | Results | Publications |
|---|---|---|
| 2020-01-18 11:01:00 | Pbp1 binds to TORC1 specifically during respiratory growth, but utilizes an additional methionine-rich, low complexity (LC) region to inhibit TORC1. This LC region causes phase separation, forms reversible fibrils, and enables self-association into assemblies required for TORC1 inhibition. | 30982600 |
| 2020-01-18 11:01:00 | The Pbp1 methionine residues are sensitive to hydrogen peroxide mediated oxidation in vitro and in living cells. Methionine oxidation melts Pbp1 liquid-like droplets in a manner reversed by methionine sulfoxide reductase enzymes. | 30982603 |
| 2017-10-21 10:28:00 | Quantitative global proteomics of yeast PBP1 deletion mutants and their stress responses identifies glucose metabolism, mitochondrial, and stress granule changes. | 27966978 |
| 2015-10-03 10:31:00 | Snf1 phosphorylates and activates Psk1. Once activated, Psk1 may phosphorylate Pbp1, which is known to stimulate stress granule formation and inhibit TORC1 through sequestration. Thus, Psk1 is a link between energy status and cell growth/proliferation. | 25428989 |
| 2013-10-26 10:59:00 | Pbp1 is involved in the Ccr4- and Khd1-mediated regulation of cell growth through the association with Rpl12a and Rpl12b. | 23563484 |
| Type | IDs |
|---|---|
| Synonymous | MRS16 |
| Gene |
UniProtKB-ID:
PBP1_YEAST
UniprotKB:
P53297
UniParc:
UPI0000131386
EMBL:
U46931,
BK006941,
Z72963
EnsemblGenome:
YGR178C
KO:
sce:YGR178C
|
| Nucleutide sequences |
EMBL-CDS:
AAB94294.1,
CAA97204.1,
DAA08273.1
EnsemblGenome_TRS:
YGR178C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YGR178C
RefSeq:
NP_011694.3
|
| Others |
UniRef100:
UniRef100_P53297
UniRef90:
UniRef90_P53297
UniRef50:
UniRef50_P53297
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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