| Type | Description |
|---|---|
| Definition | thiamine thiazole synthase |
| Date | Results | Publications |
|---|---|---|
| 2010-01-21 00:00:00 | structure of thiazole synthase (Thi4) from Saccharomyces cerevisiae was determined to 1.8 A resolution | 16964967 |
| 2010-01-21 00:00:00 | observations confirm NAD as the substrate for THI4 and elucidate the early steps of this unique biosynthesis of the thiazole moiety of thiamin in eukaryotes | 17309261 |
| 2010-01-21 00:00:00 | CyPBP37 is characterized as an abundant cytosolic protein homologous with yeast Thi4, and with a functional NAD-binding site. | 15544818 |
| Type | IDs |
|---|---|
| Synonymous | ESP35, MOL1 |
| Gene |
UniProtKB-ID:
THI4_YEAST
UniprotKB:
P32318
UniParc:
UPI0000136D8C
EMBL:
Z72930,
BK006941,
X61669,
X85807,
Z72929
EnsemblGenome:
YGR144W
KO:
sce:YGR144W
|
| Nucleutide sequences |
EMBL-CDS:
DAA08235.1,
CAA97157.1,
CAA59802.1,
CAA97159.1,
CAA43843.1
Gene_ORFName:
G6620
EnsemblGenome_TRS:
YGR144W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YGR144W
RefSeq:
NP_011660.1
|
| Others |
UniRef100:
UniRef100_P32318
UniRef90:
UniRef90_P32318
UniRef50:
UniRef50_P32318
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 33115720 |
G3 (Bethesda) Elsbeth Sanders , Phoebe A Nguyen , Cody M Rogers , Matthew L Bochman |
2020-12-03 | - |
| 29674565 |
Systematic analysis of complex genetic interactions. Science Elena Kuzmin , Benjamin VanderSluis , Wen Wang , Guihong Tan , Raamesh Deshpande , Yiqun Chen , Matej Usaj , Attila Balint , Mojca Mattiazzi Usaj , Jolanda van Leeuwen , Elizabeth N Koch , Carles Pons , Andrius J Dagilis , Michael Pryszlak , Jason Zi Yang Wang , Julia Hanchard , Margot Riggi , Kaicong Xu , Hamed Heydari , Bryan-Joseph San Luis , Ermira Shuteriqi , Hongwei Zhu , Nydia Van Dyk , Sara Sharifpoor , Michael Costanzo , Robbie Loewith , Amy Caudy , Daniel Bolnick , Grant W Brown , Brenda J Andrews , Charles Boone , Chad L Myers |
2018-04-20 | - |
| 27708008 |
A global genetic interaction network maps a wiring diagram of cellular function. Science Michael Costanzo , Benjamin VanderSluis , Elizabeth N Koch , Anastasia Baryshnikova , Carles Pons , Guihong Tan , Wen Wang , Matej Usaj , Julia Hanchard , Susan D Lee , Vicent Pelechano , Erin B Styles , Maximilian Billmann , Jolanda van Leeuwen , Nydia van Dyk , Zhen-Yuan Lin , Elena Kuzmin , Justin Nelson , Jeff S Piotrowski , Tharan Srikumar , Sondra Bahr , Yiqun Chen , Raamesh Deshpande , Christoph F Kurat , Sheena C Li , Zhijian Li , Mojca Mattiazzi Usaj , Hiroki Okada , Natasha Pascoe , Bryan-Joseph San Luis , Sara Sharifpoor , Emira Shuteriqi , Scott W Simpkins , Jamie Snider , Harsha Garadi Suresh , Yizhao Tan , Hongwei Zhu , Noel Malod-Dognin , Vuk Janjic , Natasa Przulj , Olga G Troyanskaya , Igor Stagljar , Tian Xia , Yoshikazu Ohya , Anne-Claude Gingras , Brian Raught , Michael Boutros , Lars M Steinmetz , Claire L Moore , Adam P Rosebrock , Amy A Caudy , Chad L Myers , Brenda Andrews , Charles Boone |
2016-09-23 | - |
| 22031445 |
Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase. Nature Abhishek Chatterjee , N Dinuka Abeydeera , Shridhar Bale , Pei-Jing Pai , Pieter C Dorrestein , David H Russell , Steven E Ealick , Tadhg P Begley |
2011-10-27 |
THI4
|
| 20971897 |
A maize thiamine auxotroph is defective in shoot meristem maintenance. Plant Cell John B Woodward , N Dinuka Abeydeera , Debamita Paul , Kimberly Phillips , Maria Rapala-Kozik , Michael Freeling , Tadhg P Begley , Steven E Ealick , Paula McSteen , Michael J Scanlon |
2010-10-01 | - |
| 20093466 |
The genetic landscape of a cell. Science Michael Costanzo , Anastasia Baryshnikova , Jeremy Bellay , Yungil Kim , Eric D Spear , Carolyn S Sevier , Huiming Ding , Judice L Y Koh , Kiana Toufighi , Sara Mostafavi , Jeany Prinz , Robert P St Onge , Benjamin VanderSluis , Taras Makhnevych , Franco J Vizeacoumar , Solmaz Alizadeh , Sondra Bahr , Renee L Brost , Yiqun Chen , Murat Cokol , Raamesh Deshpande , Zhijian Li , Zhen-Yuan Lin , Wendy Liang , Michaela Marback , Jadine Paw , Bryan-Joseph San Luis , Ermira Shuteriqi , Amy Hin Yan Tong , Nydia van Dyk , Iain M Wallace , Joseph A Whitney , Matthew T Weirauch , Guoqing Zhong , Hongwei Zhu , Walid A Houry , Michael Brudno , Sasan Ragibizadeh , Balázs Papp , Csaba Pál , Frederick P Roth , Guri Giaever , Corey Nislow , Olga G Troyanskaya , Howard Bussey , Gary D Bader , Anne-Claude Gingras , Quaid D Morris , Philip M Kim , Chris A Kaiser , Chad L Myers , Brenda J Andrews , Charles Boone |
2010-01-22 | - |
| 18719252 |
High-quality binary protein interaction map of the yeast interactome network. Science Haiyuan Yu , Pascal Braun , Muhammed A Yildirim , Irma Lemmens , Kavitha Venkatesan , Julie Sahalie , Tomoko Hirozane-Kishikawa , Fana Gebreab , Na Li , Nicolas Simonis , Tong Hao , Jean-François Rual , Amélie Dricot , Alexei Vazquez , Ryan R Murray , Christophe Simon , Leah Tardivo , Stanley Tam , Nenad Svrzikapa , Changyu Fan , Anne-Sophie de Smet , Adriana Motyl , Michael E Hudson , Juyong Park , Xiaofeng Xin , Michael E Cusick , Troy Moore , Charlie Boone , Michael Snyder , Frederick P Roth , Albert-László Barabási , Jan Tavernier , David E Hill , Marc Vidal |
2008-10-03 |
YJL077W-B,
YPR159C-A,
YLL017W,
HMLALPHA1,
KRR1,
PEX34,
GID7,
MXR2,
RNQ1,
YCL021W-A,
YCP4,
YCR007C,
RVS161,
PET18,
MAK31,
HSP30,
SLM5,
RHB1,
SYP1,
YCR051W,
TAH1,
BUD31,
HCM1,
ATG15,
SSK22,
TRX3,
CSM1,
ABP1,
ADH7,
RDS1,
SNO3,
SNZ3,
RGD2,
SEC53,
OTU1,
LAM5,
ACT1,
YPT1,
TUB2,
CAK1,
CAF16,
EPL1,
SMX2,
GNA1,
WWM1,
CDC4,
NIC96,
FAR7,
LSB3,
ECO1,
PHO4,
IRC6,
BNA6,
UBI4,
PRP19,
HIF1,
KNS1,
EMC6,
PSR1,
GTT2,
JLP1,
LDB18,
RPL8B,
ATG10,
DNM1,
SSK1,
TEN1,
LOT6,
BRE2,
MEU1,
IRC25,
UBR2,
SED5,
YLR031W,
RAD5,
YLR036C,
SHM2,
LAM6,
SRL2,
ALT1,
KIN2,
CHA4,
YLR108C,
AVL9,
CLF1,
SRN2,
USB1,
SLX4,
SPE4,
ASP3-2,
YLR173W,
CBF5,
YLR177W,
SAM1,
VTA1,
EMG1,
ENT2,
SEC13,
TUB4
|
| 18087042 |
Association of yeast Upf1p with direct substrates of the NMD pathway. Proc Natl Acad Sci U S A Marcus J O Johansson , Feng He , Phyllis Spatrick , Chunfang Li , Allan Jacobson |
2007-12-26 | - |
| 17923092 |
Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches. Cell Amie J McClellan , Yu Xia , Adam M Deutschbauer , Ron W Davis , Mark Gerstein , Judith Frydman |
2007-10-05 |
VAC17,
SRO9,
NFS1,
BUD3,
SGF29,
STP22,
LDB16,
YCL002C,
YCL001W-A,
NPP1,
RBK1,
THR4,
BUD31,
HCM1,
ATG15,
PAT1,
TUP1,
CDC50,
GIT1,
RDS1,
YFL054C,
YFL051C,
ALR2,
OTU1,
LAM5,
ACT1,
TUB2,
RPL22B,
HAC1,
BST1,
GAT1,
PAU5,
SMX2,
IES1,
HXT10,
CDC4,
SEC4,
SPB4,
DEG1,
LOC1,
YFR006W,
YFH7,
GCN20,
UBP6,
MIC19,
IOC3,
CMK1,
YFR016C,
IGD1,
YFR018C,
ROG3,
PES4,
ECO1,
CDC26,
ERJ5,
IRC6,
DUG1,
RET2,
VPS13,
YLL032C,
GPI13,
FRA1,
PAU17,
SPA2,
DPS1,
EMC6,
SOF1,
COX17,
ORC3,
SFI1,
RTT109,
AYT1,
COF1,
RPL8B,
FPS1,
CMS1,
SSK1,
YLR012C,
SDO1,
SNF7,
YLR031W,
PDC1,
IES3,
SPT8,
PER33,
XYL2,
BUD20,
SIC1,
CSF1,
XDJ1,
NYV1,
GIS3,
IOC2,
CHA4,
ICT1,
CCW12,
SRN2,
USB1,
DPH6
|
| 17309261 |
Biosynthesis of thiamin thiazole in eukaryotes: conversion of NAD to an advanced intermediate. J. Am. Chem. Soc. Abhishek Chatterjee , Christopher T Jurgenson , Frank C Schroeder , Steven E Ealick , Tadhg P Begley |
2007-03-14 |
THI4
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员