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8530 CST7

8530

CST7

cystatin F

protein-coding

Homo sapiens

基因描述

Type Description
Definition cystatin F

研究结论

Date Results Publications
2019-12-28 10:51:00 Cystatin F was identified as the key subunit of family 2 cystatins in survival analysis. Pancreatic ductal adenocarcinoma (PDAC) patients who harbored a higher expression level of CST7 had a lower risk in overall survival. The prognostic nomogram indicated that the CST7 expression model effectively predicted the outcomes of patients with earlystage PDAC. 31059105
2018-12-29 10:16:00 during monocyte to macrophage differentiation, the endosomal/lysosomal proteolytic activity can be regulated by cystatin F whose expression is under the control of transcriptional factor C/EBP alpha. 30033148
2012-06-23 11:53:00 Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells. 22365146
2012-02-25 11:24:00 Transgenic cystatin F is expressed in model mice only during demyelination; in chronic demyelination, remyelinating ability is lost. 21344476
2010-01-21 00:00:00 Data demonstrate the addition of N-linked sugars to an Asn-X-Cys motif in cystatin F and suggest that the mannose 6-phosphate sorting machinery is used to divert cystatin F from the secretory pathway and to mediate its uptake from extracellular pools. 19192250

名称对应

Type IDs
Synonymous CMAP
Gene
UniProtKB-ID: CYTF_HUMAN
UniprotKB: O76096
UniParc: UPI0000001CA0
EMBL: AJ510168, AJ510169, AL035661, AF036342, AB015225, AB029636, AJ510170, BC015507, BT009825, AJ510167, CR541860, CR541878, AF031824
Ensembl: ENSG00000077984
KO: hsa:8530
Nucleutide sequences
EMBL-CDS: AAH15507.1, CAG46658.1, BAA34941.1, CAG46676.1, AAC39788.1, BAB11886.1, AAC35747.1, AAP88827.1, CAD52872.1
Ensembl_TRS: ENST00000480798
Protein sequencees
Ensembl_PRO: ENSP00000420384
RefSeq: NP_003641.3
Others
UniRef100: UniRef100_O76096
UniRef90: UniRef90_O76096
UniRef50: UniRef50_O76096
UniGene: Hs.143212
CCDS: CCDS13165.2

全选

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