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852991 TEL2

852991

TEL2

Tel2p

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition Tel2p

研究结论

Date Results Publications
2018-12-22 12:06:00 It has become apparent in the last decade that the stability or maturation of the PIKK family members depends on a molecular chaperone called the Tel2-Tti1-Tti2 (TTT) complex 29470645
2017-09-23 12:30:00 Our findings provide a model in which two different Tel2 pathways promote protein stabilization of Mec1 and Tel1 in budding yeast. 28827813
2015-05-16 10:47:00 present a structural and biochemical analysis of Hsp90-Tah1-Pih1, Hsp90-Spagh, and Pih1D1-Tel2 complexes that reveal a domain in Pih1D1 specific for binding CK2 phosphorylation sites 24794838
2012-06-09 10:26:00 Existence of a novel role for Tel2, namely in transcription, possibly in cooperation with Rvb2 and involving the existence of physical interactions with the Med15/Gal11 Mediator subunit. 22291956
2012-04-07 10:27:00 these findings demonstrate separation of function explainable by differential binding of Tel2 to its PIKK substrates Tel1 or Tor1/Tor2 and thus a critical contribution of Tel2 to the interface that links various PIKKs to this chaperone complex. 22227188

名称对应

Type IDs
Gene
UniProtKB-ID: TEL2_YEAST
UniprotKB: P53038
UniParc: UPI0000047282
EMBL: U38538, Z72884, BK006941
EnsemblGenome: YGR099W
KO: sce:YGR099W
Nucleutide sequences
EMBL-CDS: CAA97102.1, AAB60317.1, DAA08192.1
EnsemblGenome_TRS: YGR099W_mRNA
Protein sequencees
EnsemblGenome_PRO: YGR099W
RefSeq: NP_011613.3
Others
UniRef100: UniRef100_P53038
UniRef90: UniRef90_P53038
UniRef50: UniRef50_P53038

全选

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研究热度

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