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852876 PMA1

852876

PMA1

H(+)-exporting P2-type ATPase PMA1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition H(+)-exporting P2-type ATPase PMA1

研究结论

Date Results Publications
2019-06-29 11:31:00 Results show that H(+) influx coupled to nutrient uptake stimulates Target of Rapamycin Complex 1 (TORC1) activity and that plasma membrane H(+)-ATPase (Pma1) is a key actor in this mechanism. 29570051
2018-06-16 11:20:00 Pma1 physically interacts with Exo1. 28727280
2017-03-25 11:42:00 These data confirm the important role of Asp739 and Arg811 residues for the biogenesis and function of the enzyme, suggesting their importance for defining H+ transport determinants but ruling out, however, the existence of a strong ionic bond (salt bridge) between these two residues and/or importance of such bridge for structure-function relationships in Pma1 H+-ATPase. 28320286
2017-03-18 11:04:00 These results indicate changes in the cell lipid composition. Western blot analysis showed the induction of Pma1 level by IM. RT-PCR revealed an increased PMA1 expression after IM treatment. 27966483
2017-02-18 11:38:00 Therefore, H(+) extrusion by Pma1 may be important for Ca(2+) influx through Cch1/Mid1. These results suggest that Pma1 interacts physically with Cch1/Mid1 Ca(2+) channels to enhance their activity via its H(+) -pumping activity 27935186

名称对应

Type IDs
Synonymous KTI10
Gene
UniProtKB-ID: PMA1_YEAST
UniprotKB: P05030
UniParc: UPI0000131C9D
EMBL: BK006941, Z72530, X03534
EnsemblGenome: YGL008C
KO: sce:YGL008C
Nucleutide sequences
EMBL-CDS: DAA08090.1, CAA96708.1, CAA27237.1
EnsemblGenome_TRS: YGL008C_mRNA
Protein sequencees
EnsemblGenome_PRO: YGL008C
RefSeq: NP_011507.1
Others
UniRef100: UniRef100_P05030
UniRef90: UniRef90_P05030
UniRef50: UniRef50_P05030

全选

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研究热度

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