| Type | Description |
|---|---|
| Definition | J-type chaperone JAC1 |
| Date | Results | Publications |
|---|---|---|
| 2017-01-14 11:52:00 | Isu is a substrate of the Lon-type protease and that it is protected from degradation by Jac1, the J-protein Hsp70 cochaperone that functions in cluster transfer from Isu. Jac1 variants known to be defective in interaction with Isu were also defective in protecting Isu from degradation. | 26842892 |
| 2016-05-07 11:00:00 | Studied the structure and dynamics of the yeast Isu1-Jac1 complex. | 25973573 |
| 2013-12-07 11:54:00 | Competition between Jac1 and Nfs1 for Isu binding plays an important role in transitioning the iron/Sulfur cluster biogenesis machinery. | 23946486 |
| 2012-07-14 10:34:00 | Jac1:Isu1 interaction plays an indispensable role in the essential process of mitochondrial Fe-S cluster biogenesis | 22306468 |
| 2010-01-21 00:00:00 | formation of a Jac1-Isu1 complex can overcome a lowered affinity of Ssq1 for Isu in vivo as well as in vitro | 15958384 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
JAC1_YEAST
UniprotKB:
P53193
UniParc:
UPI000013B023
EMBL:
Z72540,
BK006941,
AY558479
EnsemblGenome:
YGL018C
KO:
sce:YGL018C
|
| Nucleutide sequences |
EMBL-CDS:
CAA96718.1,
DAA08080.1,
AAS56805.1
EnsemblGenome_TRS:
YGL018C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YGL018C
RefSeq:
NP_011497.1
|
| Others |
UniRef100:
UniRef100_P53193
UniRef90:
UniRef90_P53193
UniRef50:
UniRef50_P53193
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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