| Type | Description |
|---|---|
| Definition | nicotinamidase |
| Date | Results | Publications |
|---|---|---|
| 2017-05-27 10:48:00 | Enhanced resistance was also independent of the nicotinamide salvage pathway, which uses nicotinamide as a substrate to generate NAD+, and of a DNA damage-induced increase in the salvage enzyme Pnc1 | 27527516 |
| 2016-04-30 10:41:00 | Stress exposure results in increased peroxisomal levels of yeast Pnc1 and Gpd1, which are imported via a piggy-backing mechanism. | 26516056 |
| 2014-09-27 12:49:00 | In this paper, the catalytic mechanism of Pnc1 has been investigated by using a combined quantum-mechanical/molecular-mechanical (QM/MM) approach based on the recently obtained crystal structure of Pnc1. | 24413890 |
| 2012-03-10 10:25:00 | The overall kinetic mechanism of eukaryotic nicotinamidase from S. cerevisiae (Pnc1) is established through product inhibition analysis, also demonstrating that nicotinamide analogues are Pnc1 inhibitors. | 22229411 |
| 2010-01-21 00:00:00 | overall data showed that PNC1 is a biomarker of mRNA mistranslation and protein misfolding and that PNC1-GFP fusions can be used to monitor these two important biological phenomena in vivo | 19381334 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PNC1_YEAST
UniprotKB:
P53184
UniParc:
UPI000013B04C
EMBL:
BK006941,
Z72559,
AY558481
EnsemblGenome:
YGL037C
KO:
sce:YGL037C
|
| Nucleutide sequences |
EMBL-CDS:
CAA96739.1,
AAS56807.1,
DAA08063.1
EnsemblGenome_TRS:
YGL037C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YGL037C
RefSeq:
NP_011478.3
|
| Others |
UniRef100:
UniRef100_P53184
UniRef90:
UniRef90_P53184
UniRef50:
UniRef50_P53184
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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