| Type | Description |
|---|---|
| Definition | translation initiation factor eIF4G |
| Date | Results | Publications |
|---|---|---|
| 2019-07-06 10:32:00 | Crystal structures of a fungal eIF4E-eIF4G complex were determined. The canonical and non-canonical motifs in 4E-BPs and eIF4G contribute differently to the affinity for eIF4E. Highly specialized structural motifs do exist and serve to modulate the affinity of protein-protein interactions that regulate cap-dependent translation initiation in fungi. | 30053226 |
| 2018-01-27 11:43:00 | depleting eukaryotic translation initiation factor 4G (eIF4G), the scaffold subunit of eukaryotic translation initiation factor 4F (eIF4F), preferentially impacts short mRNAs with strong closed-loop potential and unstructured exactly the opposite features associated with hyperdependence on the eIF4B/helicases. | 27601676 |
| 2017-11-04 11:12:00 | These results reveal and characterize an unexpected interdependence between the two RNA helicases and eIF4G, and suggest that Ded1p is an integral part of eIF4F, the complex comprising eIF4G, eIF4A, and eIF4E. | 27494274 |
| 2010-10-04 12:33:00 | Data show that that deletion of eIF4G1, but not eIF4G2, impairs growth and global translation initiation rates. | 20161741 |
| 2010-04-19 11:44:00 | involvement of yeast eIF4G in pre-mRNA metabolism; Tif4631p and Tif4632p interact efficiently with U1 snRNA; Tif4631p and Tif4632p associate with protein components of the splicing machinery, namely Snu71p and Prp11p. | 19838078 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
IF4F2_YEAST
UniprotKB:
P39936
UniParc:
UPI0000052DEA
EMBL:
L16924,
BK006941,
Z72571
EnsemblGenome:
YGL049C
KO:
sce:YGL049C
|
| Nucleutide sequences |
EMBL-CDS:
CAA96751.1,
AAA18474.1,
DAA08052.1
EnsemblGenome_TRS:
YGL049C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YGL049C
RefSeq:
NP_011466.1
|
| Others |
UniRef100:
UniRef100_P39936
UniRef90:
UniRef90_P39936
UniRef50:
UniRef50_P39935
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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