| Type | Description |
|---|---|
| Definition | stearoyl-CoA 9-desaturase |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 14:06:00 | OLE1, which was identified as the only gene with a differential single-nucleotide polymorphism mutation site related to fatty acid metabolism, was significantly changed in response to ethanol. The role of OLE1 in membrane fluidity was positively validated in its overexpressed transformants. OLE1 lowered the rate of decline in membrane fluidity and thus enabled the yeast to better fight the deleterious effects of ethanol. | 31540996 |
| 2020-05-30 10:06:00 | A crucial role of OLE1 in thermotolerance was identified: the overexpression of OLE1 increased fatty acid unsaturation, and thereby helped counter lipid peroxidation caused by heat stress, rendering the yeast thermotolerant. | 30394685 |
| 2020-02-22 10:37:00 | The OAF1 and OLE1 variants showed a non-additive genetic interaction, and affected cellular lipid metabolism. These results demonstrate that the molecular basis of trans-regulatory variation is diverse, highlighting the challenges in predicting which natural genetic variants affect gene expression | 31738765 |
| 2019-09-28 12:47:00 | The results indicate that overexpression of OLE1 reduces oxidative stress induced by cadmium possibly through the inhibition of lipid peroxidation and protection of the cytoplasmic membrane from damage in yeast cells. | 30085078 |
| 2018-07-14 10:06:00 | Mga2 also activates the transcription of its own mRNA in response to iron deficiency, hypoxia, low temperature and low UFAs. MGA2 up-regulation contributes to increase OLE1 expression in these situations. | 29627385 |
| Type | IDs |
|---|---|
| Synonymous | MDM2 |
| Gene |
UniProtKB-ID:
ACO1_YEAST
UniprotKB:
P21147
UniParc:
UPI00001252C3
EMBL:
Z72577,
BK006941,
J05676,
AY693010
EnsemblGenome:
YGL055W
KO:
sce:YGL055W
|
| Nucleutide sequences |
EMBL-CDS:
CAA96757.1,
DAA08047.1,
AAA34826.1,
AAT93029.1
EnsemblGenome_TRS:
YGL055W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YGL055W
RefSeq:
NP_011460.3
|
| Others |
UniRef100:
UniRef100_P21147
UniRef90:
UniRef90_P21147
UniRef50:
UniRef50_P21147
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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