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8528 DDO

8528

DDO

D-aspartate oxidase

protein-coding

Homo sapiens

基因描述

Type Description
Definition D-aspartate oxidase

研究结论

Date Results Publications
2020-07-25 12:05:00 three-dimensional structural analysis contributes insights into the structure-function relationships of human DASPO 31914658
2019-11-02 10:28:00 The strongest DNA methylation changes in atopic asthma were detected in the promoter region of SMAD3 gene at chr 15q22.33 and introns of DDO/METTL24 genes at 6q21. 29729188
2017-11-18 11:31:00 This study is the first to report robust age associations for DNA methylation in MYOF and DDO, both of which have plausible functional roles in aging 28255110
2017-10-28 12:17:00 SNPSs R216Q and S308N reduce enzyme activity towards acidic d-amino acids, decrease the binding affinity for the coenzyme flavin adenine dinucleotide and decrease the temperature stability. Expression of DDO genes carrying the R216Q or S308N SNP substitutions may increase the d-aspartate content in humans and alter homeostasis of several other amino acids. 28629864
2015-12-19 12:10:00 Characterization of the enzymatic and structural properties of human D-aspartate oxidase and comparison with those of the rat and mouse enzymes 25747990

名称对应

Type IDs
Synonymous DASOX, DDO-1, DDO-2
Gene
UniProtKB-ID: OXDD_HUMAN
UniprotKB: Q99489
UniParc: UPI0000231CB1, UPI000006D9AB, UPI000002B038, UPI0000130F64
EMBL: CH471051, D89858, DN990727, BC032786, AL050350, AK293029
Ensembl: ENSG00000203797
KO: hsa:8528
Nucleutide sequences
EMBL-CDS: EAW48316.1, BAF85718.1, AAH32786.3, BAA14031.1, EAW48317.1
Ensembl_TRS: ENST00000368923, ENST00000368924, ENST00000674206
Protein sequencees
Ensembl_PRO: ENSP00000357920, ENSP00000357919, ENSP00000501443
RefSeq: NP_001355102.1, NP_001355104.1, NP_001355101.1, NP_001355100.1, NP_004023.3, NP_001359037.1, NP_001355099.1, NP_001355103.1
Others
UniRef100: UniRef100_Q99489
UniRef90: UniRef90_Q99489
UniRef50: UniRef50_Q99489
UniGene: Hs.591348
CCDS: CCDS5082.1, CCDS5083.1

全选

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