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852793 MMS2

852793

MMS2

E2 ubiquitin-conjugating protein MMS2

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition E2 ubiquitin-conjugating protein MMS2

研究结论

Date Results Publications
2015-12-19 12:03:00 The error-free post-replication repair pathway mediated by Mms2p suppresses dimer-induced recombination between homologs, possibly by channeling replication-blocking lesions into recombination between sister chromatids. 25738287
2011-08-13 10:16:00 The authors demonstrate that in the absence of PCNA SUMOylation, Mms2-Ubc13 and Rad5 may, independently of each other, function in the stimulation of translesion DNA synthesis. 21362066
2010-01-21 12:36:00 Rad6-Rad18 and Ubc13-Mms2-Rad5 act sequentially and mediate proliferating cell nuclear antigen poly-ubiquitylation by stepwise addition of ubiquitin monomers. 19851286
2010-01-21 00:00:00 The structure reveals the key role of Mms2 in allowing selective insertion of Lys63 into the Ubc13 active site and suggests a molecular model for polyubiquitin chain elongation. 16980971
2010-01-21 00:00:00 In contrast to the role of Rad5 in postreplicational repair, however, where its function is coupled with that of Mms2-Ubc13, Rad5 function in translesion synthesis would be largely independent of this ubiquitin-conjugating enzyme complex 16908531

名称对应

Type IDs
Gene
UniProtKB-ID: MMS2_YEAST
UniprotKB: P53152
UniParc: UPI000012F28C
EMBL: Z72609, BK006941, U66724
EnsemblGenome: YGL087C
KO: sce:YGL087C
Nucleutide sequences
EMBL-CDS: DAA08018.1, CAA96792.1, AAC24241.1
EnsemblGenome_TRS: YGL087C_mRNA
Protein sequencees
EnsemblGenome_PRO: YGL087C
RefSeq: NP_011428.1
Others
UniRef100: UniRef100_P53152
UniRef90: UniRef90_P53152
UniRef50: UniRef50_P53152

全选

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研究热度

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