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852790 LIF1

852790

LIF1

Lif1p

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition Lif1p

研究结论

Date Results Publications
2012-08-04 11:22:00 Lif1 phosphorylation at Ser261 is probably involved in micro-homology-dependent end joining associated with producing single-stranded DSB ends that are formed by Sae2 as early intermediates in the homologous recombination pathway. 22563681
2010-01-21 00:00:00 Dnl4-Lif1 plays an important part in determining repair pathway choice by participating at an early stage of DSB engagement in addition to providing the DNA ligase activity that completes nonhomologous end joining. 17589524
2010-01-21 00:00:00 globular head of XRCC4/Lif1 interacted with N- and C-terminal domains of XLF and Nej1 17567543
2010-01-21 00:00:00 Preliminary functional and structural studies on the Nej1p-Lif1p complex suggest that the proteins stably co-purify and the complex binds DNA with a higher affinity than each independent component 17765666
2010-01-21 00:00:00 Data show that a lack of any of the NHEJ proteins Yku (Yku70-Yku80), Lif1 or DNA ligase IV (Dnl4) increases 5' DSB end degradation in G1 phase, with ykuDelta cells showing the strongest effect. 18600234

名称对应

Type IDs
Gene
UniProtKB-ID: LIF1_YEAST
UniprotKB: P53150
UniParc: UPI000013B0D3
EMBL: BK006941, AY723807, Z72612
EnsemblGenome: YGL090W
KO: sce:YGL090W
Nucleutide sequences
EMBL-CDS: AAU09724.1, DAA08016.1, CAA96796.1
EnsemblGenome_TRS: YGL090W_mRNA
Protein sequencees
EnsemblGenome_PRO: YGL090W
RefSeq: NP_011425.1
Others
UniRef100: UniRef100_P53150
UniRef90: UniRef90_P53150
UniRef50: UniRef50_P53150

全选

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研究热度

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