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852728 INO80

852728

INO80

chromatin-remodeling ATPase INO80

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition chromatin-remodeling ATPase INO80

研究结论

Date Results Publications
2019-10-05 12:24:00 Arp8 engages N-actin in a manner distinct from that of other actin-fold proteins and thereby specifies recruitment of the Arp4-N-actin heterodimer to a segmented scaffold of the helicase-SANT-associated (HSA) domain of Ino80 30177756
2019-06-08 12:33:00 Binding of INO80 to these genes is cell cycle regulated, with a maximum binding preceding their transcription and accumulation of their mRNAs. In fact, the INO80 complex is required to fully and timely activate the transcription of these genes 30134042
2019-03-02 11:32:00 we report that Isw2 and Ino80 promote efficient firing of the ribosomal origin of replication and facilitate the regulated increase of rDNA repeat copy number. This work significantly expands our understanding of the importance of ATP-dependent chromatin remodeling for rDNA biology. 30355728
2019-01-05 12:08:00 indicate that INO80 is a highly processive remodeling motor that is tightly regulated by both substrate cues and non-catalytic subunits 29452642
2018-11-24 10:10:00 INO80 translocates along DNA at the H2A-H2B interface of nucleosomes and persistently displaces DNA from the surface of H2A-H2B. The data suggest that INO80 has a mechanism for dimer exchange that is distinct from other chromatin remodellers including its paralogue SWR1. 28604691

名称对应

Type IDs
Gene
UniProtKB-ID: INO80_YEAST
UniprotKB: P53115
UniParc: UPI0000053052
EMBL: Z72672, Z48618, BK006941, X99960
EnsemblGenome: YGL150C
KO: sce:YGL150C
Nucleutide sequences
EMBL-CDS: CAA88537.1, CAA68224.1, CAA96861.1, DAA07961.1
Gene_ORFName: G1880
EnsemblGenome_TRS: YGL150C_mRNA
Protein sequencees
EnsemblGenome_PRO: YGL150C
RefSeq: NP_011365.1
Others
UniRef100: UniRef100_P53115
UniRef90: UniRef90_P53115
UniRef50: UniRef50_P53115

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