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852713 RAD54

852713

RAD54

DNA-dependent ATPase RAD54

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition DNA-dependent ATPase RAD54

研究结论

Date Results Publications
2021-04-17 13:16:00 Rad54 and Rdh54 occupy spatially and functionally distinct sites within the Rad51-ssDNA presynaptic complex. 32790929
2020-01-04 10:09:00 Data suggest that recombinase RAD51 (Rad51)/DNA-dependent ATPase RAD54 (Rad54) form a functional unit operating in homology search, synaptic complex and D-loop formation. 31492866
2017-05-27 10:20:00 ad51-mediated recombination occurring in the absence of Hed1 phosphorylation results in a significant increase in non-exchange chromosomes despite wild-type levels of crossovers, confirming previous results indicating a defect in crossover assurance. We propose that Rad51 function in meiosis is regulated in part by the coordinated phosphorylation of Rad54 and Hed1 by Mek1 27483004
2014-10-04 10:58:00 Our study identified a novel sequence motif critical for Rad54 function and showed that even perfect matches to the PIP box consensus may not necessarily identify PCNA interaction sites. 24358152
2014-05-10 11:37:00 Rad54 acts as an hDNA pump that drives D loop formation while simultaneously removing Rad51 from hDNA, consolidating both ATP-dependent activities of Rad54 into a single mechanistic step. 24486020

名称对应

Type IDs
Synonymous XRS1
Gene
UniProtKB-ID: RAD54_YEAST
UniprotKB: P32863
UniParc: UPI0000133038
EMBL: M63232, Z72685, Z48618, BK006941
EnsemblGenome: YGL163C
KO: sce:YGL163C
Nucleutide sequences
EMBL-CDS: CAA88534.1, CAA96875.1, AAA34949.1, DAA07949.1
Gene_ORFName: G1821
EnsemblGenome_TRS: YGL163C_mRNA
Protein sequencees
EnsemblGenome_PRO: YGL163C
RefSeq: NP_011352.1
Others
UniRef100: UniRef100_P32863
UniRef90: UniRef90_P32863
UniRef50: UniRef50_P32863

全选

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研究热度

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