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852672 ARO8

852672

ARO8

bifunctional 2-aminoadipate transaminase/aromatic-amino-acid:2-oxoglutarate transaminase

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition bifunctional 2-aminoadipate transaminase/aromatic-amino-acid:2-oxoglutarate transaminase

研究结论

Date Results Publications
2019-07-20 11:44:00 Study confirmed Aro8 and Aro9 as primary kynurenine aminotransferases (KATs) in S. cerevisiae and showed that the aro8Delta aro9Delta mutant cells lack kynurenic acid (KA) and showed that aro8Delta aro9Delta cells were sensitive to high concentrations of tryptophan (Trp). While expression of ARO9 rescued the sensitivity for Trp in the aro8Delta aro9Delta double mutant, addition of KA to the medium did not. 28939805
2016-01-02 11:09:00 Deletion of ARO8 led to de novo production of phenylethanol during growth on a glucose synthetic medium. 24733517
2014-04-26 10:57:00 The aromatic aminotransferase Aro8 has been identified as an AAA-AT in Saccharomyces cerevisiae. This enzyme displays broad substrate selectivity, utilizing several amino acids and 2-oxo acids as substrates. 23893908

名称对应

Type IDs
Gene
UniProtKB-ID: ARO8_YEAST
UniprotKB: P53090
UniParc: UPI0000125F25
EMBL: Y13624, AY692962, BK006941, Z72724
EnsemblGenome: YGL202W
KO: sce:YGL202W
Nucleutide sequences
EMBL-CDS: AAT92981.1, CAA73946.1, DAA07913.1, CAA96914.1
EnsemblGenome_TRS: YGL202W_mRNA
Protein sequencees
EnsemblGenome_PRO: YGL202W
RefSeq: NP_011313.1
Others
UniRef100: UniRef100_P53090
UniRef90: UniRef90_P53090
UniRef50: UniRef50_P53090

全选

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