| Type | Description |
|---|---|
| Definition | cation-transporting P-type ATPase PCA1 |
| Date | Results | Publications |
|---|---|---|
| 2017-04-15 10:13:00 | Determined the roles for the molecular factors of ERAD in dislodging Pca1p from the endoplasmic reticulum (ER). Inactivation of the 20S proteasome leads to accumulation of ubiquitinated Pca1p in the ER membrane, suggesting a role for the proteasome in extraction of Pca1p from the ER. | 27226596 |
| 2016-12-17 11:48:00 | Data indicate that specific cysteine residues in a degron of cation-transporting P-type ATPase PCA1 (Pca1p) sense cadmium. | 27059957 |
| 2011-07-30 11:05:00 | cadmium resistance is primarily caused by an enhanced function of a metal efflux pump, PCA1. | 21483812 |
| 2010-01-21 00:00:00 | Direct cadmium sensing at the endoplasmic reticulum by a degron in Pca1 leads to an escape of Pca1 from endoplasmic reticulum-associated degradation. | 19515821 |
| 2010-01-21 00:00:00 | Overexpression or deletion of the functional allele in yeast demonstrates that PCA1 is a cadmium efflux pump | 17107946 |
| Type | IDs |
|---|---|
| Synonymous | CAD2, PAY2 |
| Gene |
UniProtKB-ID:
ATU1_YEAST
UniprotKB:
P38360
UniParc:
UPI0001F7BD3A
EMBL:
Z29332,
BK006936,
Z36164
EnsemblGenome:
YBR295W
KO:
sce:YBR295W
|
| Nucleutide sequences |
EMBL-CDS:
DAA07409.2,
CAA82529.1,
CAA85260.1
Gene_ORFName:
YBR2112
EnsemblGenome_TRS:
YBR295W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YBR295W
RefSeq:
NP_009854.2
|
| Others |
UniRef100:
UniRef100_P38360
UniRef90:
UniRef90_P38360
UniRef50:
UniRef50_P38360
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 29674565 |
Systematic analysis of complex genetic interactions. Science Elena Kuzmin , Benjamin VanderSluis , Wen Wang , Guihong Tan , Raamesh Deshpande , Yiqun Chen , Matej Usaj , Attila Balint , Mojca Mattiazzi Usaj , Jolanda van Leeuwen , Elizabeth N Koch , Carles Pons , Andrius J Dagilis , Michael Pryszlak , Jason Zi Yang Wang , Julia Hanchard , Margot Riggi , Kaicong Xu , Hamed Heydari , Bryan-Joseph San Luis , Ermira Shuteriqi , Hongwei Zhu , Nydia Van Dyk , Sara Sharifpoor , Michael Costanzo , Robbie Loewith , Amy Caudy , Daniel Bolnick , Grant W Brown , Brenda J Andrews , Charles Boone , Chad L Myers |
2018-04-20 | - |
| 29158339 |
G3 (Bethesda) Jason E Miller , Liye Zhang , Haoyang Jiang , Yunfei Li , B Franklin Pugh , Joseph C Reese |
2018-01-04 | - |
| 27863241 |
The Chromatin Remodeler ISW1 Is a Quality Control Factor that Surveys Nuclear mRNP Biogenesis. Cell Anna Babour , Qingtang Shen , Julien Dos-Santos , Struan Murray , Alexandre Gay , Drice Challal , Milo Fasken , Benoît Palancade , Anita Corbett , Domenico Libri , Jane Mellor , Catherine Dargemont |
2016-11-17 | - |
| 27708008 |
A global genetic interaction network maps a wiring diagram of cellular function. Science Michael Costanzo , Benjamin VanderSluis , Elizabeth N Koch , Anastasia Baryshnikova , Carles Pons , Guihong Tan , Wen Wang , Matej Usaj , Julia Hanchard , Susan D Lee , Vicent Pelechano , Erin B Styles , Maximilian Billmann , Jolanda van Leeuwen , Nydia van Dyk , Zhen-Yuan Lin , Elena Kuzmin , Justin Nelson , Jeff S Piotrowski , Tharan Srikumar , Sondra Bahr , Yiqun Chen , Raamesh Deshpande , Christoph F Kurat , Sheena C Li , Zhijian Li , Mojca Mattiazzi Usaj , Hiroki Okada , Natasha Pascoe , Bryan-Joseph San Luis , Sara Sharifpoor , Emira Shuteriqi , Scott W Simpkins , Jamie Snider , Harsha Garadi Suresh , Yizhao Tan , Hongwei Zhu , Noel Malod-Dognin , Vuk Janjic , Natasa Przulj , Olga G Troyanskaya , Igor Stagljar , Tian Xia , Yoshikazu Ohya , Anne-Claude Gingras , Brian Raught , Michael Boutros , Lars M Steinmetz , Claire L Moore , Adam P Rosebrock , Amy A Caudy , Chad L Myers , Brenda Andrews , Charles Boone |
2016-09-23 | - |
| 27226596 |
J Biol Chem Nathan Smith , David J Adle , Miaoyun Zhao , Xiaojuan Qin , Heejeong Kim , Jaekwon Lee |
2016-07-15 | - |
| 27059957 |
Cadmium and Secondary Structure-dependent Function of a Degron in the Pca1p Cadmium Exporter. J Biol Chem Nathan Smith , Wenzhong Wei , Miaoyun Zhao , Xiaojuan Qin , Javier Seravalli , Heejeong Kim , Jaekwon Lee |
2016-06-03 | - |
| 26668354 |
Target selection by natural and redesigned PUF proteins. Proc. Natl. Acad. Sci. U.S.A. Douglas F Porter , Yvonne Y Koh , Brett VanVeller , Ronald T Raines , Marvin Wickens |
2016-12-29 | - |
| 22997150 |
Proteomics Christopher A Jackson , Neelu Yadav , Sangwon Min , Jun Li , Eric J Milliman , Jun Qu , Yin-Chu Chen , Michael C Yu |
2012-11-01 |
YOR020W-A,
SRO9,
CDC39,
FRS2,
MSH4,
VPS13,
ARP6,
CSF1,
SWI6,
HCR1,
YLR225C,
ROM2,
AFG2,
VIP1,
FMP27,
ADE1,
HBT1,
NRP1,
RPO21,
MRP10,
SIR2,
DOS2,
RRP1,
SAC6,
SEC7,
HMO1,
YDR186C,
EBS1,
SPR28,
HTB1,
RTN1,
SSD1,
SUM1,
HXT7,
ESF1,
XRS2,
VPS74,
SIP1,
NPL3,
UBP13,
SHP1,
PEP1,
HTB2,
HMT1,
CHS2,
AKL1,
IRA1,
PGI1,
COS111,
PCA1,
MDS3,
TIF4632,
PSD2,
SNG1,
ENO1,
RTT102,
MTR4,
YJR030C,
YJU3,
MDH1,
NUP100,
SET3,
HRP1,
MDY2,
HMI1,
IRA2,
RTG1,
ISN1,
LIP5,
BFR1,
SNF2,
ALA1,
PIP2,
UTP14,
BUL2,
ORC1,
RAD52,
YML020W,
MVP1,
HOF1,
UBX4,
YMR144W,
MLH1,
PPA2,
UBP15,
TOF1,
BNI1,
CHS1,
TOM70,
RAS2,
LAP2,
YNL010W,
PRP2,
BRE5,
IQG1,
CDC60,
TBF1,
PNG1,
PMA2
|
| 22199229 |
Mol Cell Proteomics Joshua M Gilmore , Mihaela E Sardiu , Swaminathan Venkatesh , Brent Stutzman , Allison Peak , Chris W Seidel , Jerry L Workman , Laurence Florens , Michael P Washburn |
2012-04-01 | - |
| 21552543 |
PLoS Genet. Peter C Stirling , Michelle S Bloom , Tejomayee Solanki-Patil , Stephanie Smith , Payal Sipahimalani , Zhijian Li , Megan Kofoed , Shay Ben-Aroya , Kyungjae Myung , Philip Hieter |
2011-04-01 |
YLR264C-A,
YLR406C-A,
YBL071C-B,
YBR196C-A,
YGL188C-A,
YOL164W-A,
YOL097W-A,
YOL038C-A,
YIR021W-A,
YMR001C-A,
YMR175W-A,
YMR242W-A,
YMR272W-B,
YNL277W-A,
DGR1,
YPL152W-A,
YHR050W-A,
YHR175W-A,
YER175W-A,
VAC17,
MRC1,
MIC10,
SPB1,
LRE1,
GID7,
MXR2,
RRP7,
HIS4,
BIK1,
BUD3,
ILV6,
RER1,
YCL001W-A,
CDC10,
MAK31,
HSP30,
PMP1,
NPP1,
RHB1,
RPS14A,
BPH1,
SNT1,
RBK1,
PHO87,
RRT12,
YCR050C,
YCR051W,
THR4,
TAH1,
YCR061W,
HCM1,
ATG15,
IMG2,
TRX3,
YCR087C-A,
FIG2,
MSH3,
CDC39,
YCR100C,
YCR102C,
ZNF1,
SEC53,
ACT1,
TUB2,
RPO41,
MOB2,
HAC1,
BST1,
GAT1,
LPD1,
GNA1,
CDC4,
SMC1,
SEC4,
MSH4,
SPB4,
DEG1,
YPI1,
RPN11,
DCV1,
IOC3,
FAB1,
ECO1,
CDC14,
RPL29,
CDC26,
RSC8,
RMD8,
RET2,
RPN12,
IRC19,
YLL032C,
GPI13,
SOF1,
SFI1,
COF1,
LDB18,
FPS1,
TEN1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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目前还没有研究热点人员