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85259 Cnga1

85259

Cnga1

cyclic nucleotide gated channel alpha 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition cyclic nucleotide gated channel alpha 1

研究结论

Date Results Publications
2016-12-17 10:59:00 Histamine depolarizes projection neurons but not interneurons in the cerebellar nuclei via the hyperpolarization-activated cyclic nucleotide-gated (HCN) channels coupled to histamine H2 receptors. 25633097
2013-02-09 11:38:00 Insulin receptor (IR), an integral membrane protein, directly phosphorylates the CNGA1 subunit of CNG channels that in turn affects the function of these channels negatively. CNGA1 is a direct substrate of IR. 23032687
2012-10-27 10:12:00 estrogen and progesterone act in renal tissues modulating CNG-A1 and Na/K ATPase gene expression 22759964
2012-04-07 11:29:00 Data demonstrate that CNGA1 is expressed in rat cerebellar granule cells and forms functional channels. 21809342
2011-12-03 11:22:00 Data show robust CNGA1 (but not CNGA2 or CNGA3) channel expression principally in rat alveolar type I cells and suggest that CNGA1 channels mediate cGMP-stimulated, amiloride-insensitive, lung liquid absorption. 21559843

名称对应

Type IDs
Synonymous Cncg, HCN
Gene
UniProtKB-ID: CNGA1_RAT
UniprotKB: Q62927
UniParc: UPI0000127C1C
EMBL: U93851, U76220, U48803
KO: rno:85259
Nucleutide sequences
EMBL-CDS: AAC53139.1, AAC17594.1, AAA92110.1
Protein sequencees
RefSeq: NP_445949.2
Others
UniRef100: UniRef100_Q62927
UniRef90: UniRef90_Q62927
UniRef50: UniRef50_Q62927
UniGene: Rn.54534

全选

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研究热度

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