Type | Description |
---|---|
Definition | SCF ubiquitin ligase complex subunit SAF1 |
Date | Results | Publications |
---|---|---|
2015-10-10 10:54:00 | Saf1 does not require a conventional degron as do other F-box proteins but instead recognizes the catalytic site itself. | 26161950 |
2014-03-22 11:09:00 | Saf1 selectively promotes ubiquitination of the unprocessed form of the zymogen. This suggests that Saf1 is part of a pathway that targets protein precursors for proteasomal degradation. | 24389104 |
2010-01-21 00:00:00 | Saf1p is being a bona fide Skp1-Cullin-F-box subunit | 17517885 |
2010-01-21 00:00:00 | Saf1p targets Aah1p for proteasome-dependent degradation upon entry into quiescence. | 16677311 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
SAF1_YEAST
UniprotKB:
P38352
UniParc:
UPI00001D476A
EMBL:
Z36149,
X76053,
BK006936
EnsemblGenome:
YBR280C
KO:
sce:YBR280C
|
Nucleutide sequences |
EMBL-CDS:
DAA07395.1,
CAA85244.1,
CAA53643.1
Gene_ORFName:
YBR2017
EnsemblGenome_TRS:
YBR280C_mRNA
|
Protein sequencees |
EnsemblGenome_PRO:
YBR280C
RefSeq:
NP_009839.4
|
Others |
UniRef100:
UniRef100_P38352
UniRef90:
UniRef90_P38352
UniRef50:
UniRef50_P38352
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
30865586 |
Elife Rolf M Schmidt , Julia P Schessner , Georg Hh Borner , Sebastian Schuck |
2019-03-13 | - |
29158339 |
G3 (Bethesda) Jason E Miller , Liye Zhang , Haoyang Jiang , Yunfei Li , B Franklin Pugh , Joseph C Reese |
2018-01-04 | - |
27863241 |
The Chromatin Remodeler ISW1 Is a Quality Control Factor that Surveys Nuclear mRNP Biogenesis. Cell Anna Babour , Qingtang Shen , Julien Dos-Santos , Struan Murray , Alexandre Gay , Drice Challal , Milo Fasken , Benoît Palancade , Anita Corbett , Domenico Libri , Jane Mellor , Catherine Dargemont |
2016-11-17 | - |
27708008 |
A global genetic interaction network maps a wiring diagram of cellular function. Science Michael Costanzo , Benjamin VanderSluis , Elizabeth N Koch , Anastasia Baryshnikova , Carles Pons , Guihong Tan , Wen Wang , Matej Usaj , Julia Hanchard , Susan D Lee , Vicent Pelechano , Erin B Styles , Maximilian Billmann , Jolanda van Leeuwen , Nydia van Dyk , Zhen-Yuan Lin , Elena Kuzmin , Justin Nelson , Jeff S Piotrowski , Tharan Srikumar , Sondra Bahr , Yiqun Chen , Raamesh Deshpande , Christoph F Kurat , Sheena C Li , Zhijian Li , Mojca Mattiazzi Usaj , Hiroki Okada , Natasha Pascoe , Bryan-Joseph San Luis , Sara Sharifpoor , Emira Shuteriqi , Scott W Simpkins , Jamie Snider , Harsha Garadi Suresh , Yizhao Tan , Hongwei Zhu , Noel Malod-Dognin , Vuk Janjic , Natasa Przulj , Olga G Troyanskaya , Igor Stagljar , Tian Xia , Yoshikazu Ohya , Anne-Claude Gingras , Brian Raught , Michael Boutros , Lars M Steinmetz , Claire L Moore , Adam P Rosebrock , Amy A Caudy , Chad L Myers , Brenda Andrews , Charles Boone |
2016-09-23 | - |
26297725 |
G3 (Bethesda) Marion Dubarry , Conor Lawless , A Peter Banks , Simon Cockell , David Lydall |
2015-10-01 | - |
26067383 |
Metallomics Mojca Mattiazzi UÅ¡aj , Metod Prelec , Mojca Brložnik , Cecilia Primo , Tomaž Curk , Janez Å ÄanÄar , Lynne Yenush , UroÅ¡ PetroviÄ |
2015-09-01 |
AGP1,
PTC6,
YCR102C,
LAM5,
BUD27,
LPD1,
PES4,
RPL2A,
RMD8,
RPS0B,
HRT3,
SNC1,
DRS2,
RRI1,
YDL180W,
UGA3,
RPS11A,
MIX14,
MRH1,
ARO3,
EHD3,
BAP3,
PST1,
OCA6,
SWF1,
SWI5,
HOM2,
RAD30,
SIP1,
DOT1,
ECM11,
STP1,
RMT2,
PKH3,
VPS72,
PKH1,
RPL37B,
EMI2,
FMP23,
NHP6B,
FES1,
APD1,
ARL1,
MET8,
RRT2,
SAF1,
VEL1,
RMR1,
MDM34,
HOS2,
ROG1,
PAN2,
TYW3,
EFM5,
MEP1,
RSR1,
PSD2,
RPS0A,
APL6,
SLH1,
YJL181W,
MDV1,
GZF3,
SAP185,
CHM7,
YJR030C,
RAV1,
VPS55,
PTK2,
MIR1,
VBA5,
PAP2,
PTH4,
IZH2,
VAM3,
CEX1,
SYC1,
DCI1,
SLK19,
KIN4,
ENV9,
RBL2,
PNT1,
YOR289W,
YPK9,
TIM18,
SLY41,
RPL20B,
SPS4,
FAA1,
MRS2,
TYE7,
CIR2,
HAP5,
PIP2,
GDH1,
PHR1,
BNR1,
TPM2
|
26192197 |
A cytosolic network suppressing mitochondria-mediated proteostatic stress and cell death. Nature Xiaowen Wang , Xin Jie Chen |
2015-08-27 | - |
26161950 |
Prb1 Protease Activity Is Required for Its Recognition by the F-Box Protein Saf1. Biochemistry Kevin G Mark , Fernando Meza-Gutierrez , Jeffrey R Johnson , Billy W Newton , Nevan J Krogan , David P Toczyski |
2015-07-28 | - |
24470217 |
The yeast Ess1 prolyl isomerase controls Swi6 and Whi5 nuclear localization. G3 (Bethesda) David Atencio , Cassandra Barnes , Thomas M Duncan , Ian M Willis , Steven D Hanes |
2014-03-01 |
PEX34,
APA1,
GRX1,
RNQ1,
BUD3,
CWH43,
IMG2,
SSK22,
YFL051C,
FET5,
RPO41,
STE2,
AUA1,
VTC2,
MSH4,
DEG1,
QCR6,
SAP155,
BNA6,
HSP104,
RPL8B,
BRE2,
PSR2,
RPS0B,
YLR050C,
YLR053C,
OSW2,
RFU1,
CCW12,
YPS1,
DCN1,
ACF2,
SPE4,
STM1,
PCD1,
YLR173W,
TFS1,
YLR179C,
SWI6,
PEX13,
HCR1,
CRR1,
RSA3,
IRC20,
RCK2,
RED1,
NEJ1,
YLR297W,
PEX30,
VRP1,
RPL26A,
CIS1,
VPS38,
CCW14,
DUS4,
PAU4,
FUN19,
SNC1,
YAL065C,
FLC2,
HBT1,
YDL218W,
UGA3,
RPO21,
ARF2,
YDL109C,
IDP1,
RPS29B,
MBP1,
STP4,
NAT1,
DIA3,
RAD61,
NRG1,
YDR061W,
FMP16,
CPR1,
HOM2,
ARG82,
PLP1,
ATC1,
UPS3,
GTB1,
PMP3,
MRX10,
CPR5,
HNT2,
PMT7,
MCM21,
YSP2,
IRC3,
RQC1,
MRX8,
YDR338C,
YPS7,
CNL1,
CTS2,
ERD1,
SIP1
|
24389104 |
Mol. Cell Kevin G Mark , Marco Simonetta , Alessio Maiolica , Charles A Seller , David P Toczyski |
2014-01-09 |
CDC4,
TIS11,
MDM30,
CLN3,
RBG1,
HO,
STE5,
SWI5,
ATC1,
HST4,
MTH1,
GIC2,
SBE2,
YBR139W,
FZO1,
SAF1,
CDC6,
FAR1,
GRR1,
BUD4,
ASH1,
YKR045C,
PFK27,
HST3,
GAC1,
SFG1,
TYE7,
MET30,
UFO1,
CLN1,
PRC1,
PCL1,
YNL144C,
AAH1,
MET4,
CLN2,
SWI1,
ISR1,
YHR131C,
PRB1,
FIR1
|
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