| Type | Description |
|---|---|
| Definition | DNA-binding protein RIF1 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-05 11:41:00 | results indicate that Rif1 inhibits replication initiation by interacting directly with origins and suggest that Rap1-dependent sequestration of Rif1 increases its effective concentration near telomeres, while limiting its action at chromosome-internal sites. | 29694906 |
| 2019-08-10 11:52:00 | Rif1 controls telomere length by recruiting PP1 to directly suppress telomerase-mediated TG repeat lengthening. | 29529242 |
| 2019-06-08 13:21:00 | these results indicate that, in addition to controlling DNA replication initiation, budding yeast Rif1 plays an ongoing role after initiation and controls events at blocked replication forks. | 30104203 |
| 2018-10-06 10:23:00 | Rif1 SQ/TQ Cluster Domain (SCD) can modulate Rif1 function. As all Rif1 orthologs have one or more SCD domains, these results for yeast Rif1 have implications for the regulation of Rif1 function in humans and other organisms. | 29544213 |
| 2017-07-22 11:27:00 | Engagement of the Rif1 N-terminal domain with telomeres proved essential for checkpoint control and telomere length regulation. Unexpectedly, Rif1 N-terminal domain also promoted NHEJ repair at DNA breaks in yeast, revealing a conserved role of Rif1 in DNA repair. | 28604726 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
RIF1_YEAST
UniprotKB:
P29539
UniParc:
UPI0001F7BD39
EMBL:
X66501,
BK006936,
X76053,
Z36145,
Z36144
EnsemblGenome:
YBR275C
KO:
sce:YBR275C
|
| Nucleutide sequences |
EMBL-CDS:
CAA85240.1,
CAA85238.1,
DAA07391.2,
CAA47121.1,
CAA53638.1
Gene_ORFName:
YBR1743
EnsemblGenome_TRS:
YBR275C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YBR275C
RefSeq:
NP_009834.4
|
| Others |
UniRef100:
UniRef100_P29539
UniRef90:
UniRef90_P29539
UniRef50:
UniRef50_P29539
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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