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852548 RRT2

852548

RRT2

diphthamide synthase

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition diphthamide synthase

研究结论

Date Results Publications
2015-10-03 11:21:00 Dph5-catalyzed reaction generates methylated diphthine, a previously overlooked intermediate, and Dph7 is a methylesterase that hydrolyzes methylated diphthine to produce diphthine and allows the Dph6-catalyzed amidation reaction to occur. 24739148
2013-06-15 11:04:00 Through identification of Dph6 and Dph7 as components required for the amidation step of the diphthamide pathway, our work paves the way for a detailed mechanistic understanding of diphthamide formation. 23468660
2012-06-02 10:21:00 It was shown that the YBR246W gene in yeast is required for the last step of diphthamide biosynthesis, as the deletion of YBR246W leads to the accumulation of diphthine, which is the enzymatic product of the second step of the biosynthesis. 22188241
2012-02-25 10:18:00 our data indicate that a complex containing the two novel proteins, Ere1 and Ere2, mediates cargo-specific recognition by the retromer pathway. [Ere1] 21880895

名称对应

Type IDs
Synonymous DPH7, ERE1
Gene
UniProtKB-ID: DPH7_YEAST
UniprotKB: P38332
UniParc: UPI000013A291
EMBL: AY692624, Z36115, BK006936
EnsemblGenome: YBR246W
KO: sce:YBR246W
Nucleutide sequences
EMBL-CDS: DAA07362.1, AAT92643.1, CAA85209.1
Gene_ORFName: YBR1634
EnsemblGenome_TRS: YBR246W_mRNA
Protein sequencees
EnsemblGenome_PRO: YBR246W
RefSeq: NP_009805.1
Others
UniRef100: UniRef100_P38332
UniRef90: UniRef90_P38332
UniRef50: UniRef50_P38332

全选

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研究热度

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