| Type | Description |
|---|---|
| Definition | Atg12p |
| Date | Results | Publications |
|---|---|---|
| 2020-03-21 12:05:00 | Here, the authors discover a novel mechanism for the PAS targeting of Atg12-Atg5-Atg16, which is mediated by the interaction of Atg12 with the Atg1 kinase complex that serves as a scaffold for pre-autophagosomal structure organization. | 30810528 |
| 2013-11-16 11:12:00 | Atg1, Atg8 and the Atg16-Atg12-Atg5 complex were present at both the VICS and the cup-shaped IM. | 23549786 |
| 2013-07-27 11:10:00 | Atg12 functions as a binding module for Atg3, the E2 enzyme for Atg8, thus endowing Atg5 with the ability to interact with Atg3 to facilitate Atg8 lipidation. | 23238393 |
| 2013-06-15 10:58:00 | Atg12-Atg5 induces a reorientation of the cysteine residue toward the threonine residue, which enhances the conjugase activity of Atg3 | 23503366 |
| 2013-02-09 10:58:00 | It was shown that the yeast Atg5-Atg12/Atg16 complex directly binds membranes. Membrane binding is mediated by Atg5, inhibited by Atg12 and activated by Atg16. | 23064152 |
| Type | IDs |
|---|---|
| Synonymous | APG12 |
| Gene |
UniProtKB-ID:
ATG12_YEAST
UniprotKB:
P38316
UniParc:
UPI0000125C67
EMBL:
BK006936,
Z36086,
AY557706,
AB017924
EnsemblGenome:
YBR217W
KO:
sce:YBR217W
|
| Nucleutide sequences |
EMBL-CDS:
AAS56032.1,
BAA33473.1,
CAA85181.1,
DAA07333.1
Gene_ORFName:
YBR1506
EnsemblGenome_TRS:
YBR217W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YBR217W
RefSeq:
NP_009776.1
|
| Others |
UniRef100:
UniRef100_A6ZLF7
UniRef90:
UniRef90_A6ZLF7
UniRef50:
UniRef50_A6ZLF7
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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