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852501 MCM7

852501

MCM7

mini-chromosome maintenance complex protein 7

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition mini-chromosome maintenance complex protein 7

研究结论

Date Results Publications
2017-10-21 11:49:00 An intact Mcm10 coiled-coil interaction surface is important for origin melting, helicase assembly and the recruitment of Pol-alpha to Mcm2-7. 28510759
2016-06-11 12:01:00 The tethering of SCF(Dia2) to the replisome progression complex increases the efficiency of ubiquitylation of the Mcm7 subunit of CMG. Correspondingly, loss of tethering is synthetic lethal in combination with a disassembly-defective allele of CDC48. 26255844
2014-05-10 12:36:00 The data demonstrate that ORC/Cdc6 facilitates directly MCM2-7 dimerization and shows that productive MCM2-7 dimerization is essential for prereplicative complex formation. 24234446
2011-12-10 10:51:00 origin ssDNA may stimulate the formation of the CMG complex by alleviating inhibitory interactions between Sld2 with Mcm2-7. 21868389
2011-07-30 11:05:00 origin single-stranded DNA releases Sld3 from Mcm2-7, allowing GINS to bind Mcm2-7. 21460226

名称对应

Type IDs
Synonymous CDC47
Gene
UniProtKB-ID: MCM7_YEAST
UniprotKB: P38132
UniParc: UPI000012724E
EMBL: Z36071, Z21487, U14730, BK006936
EnsemblGenome: YBR202W
KO: sce:YBR202W
Nucleutide sequences
EMBL-CDS: AAA86309.1, DAA07320.2, CAA79689.1, CAA85166.1
Gene_ORFName: YBR1441
EnsemblGenome_TRS: YBR202W_mRNA
Protein sequencees
EnsemblGenome_PRO: YBR202W
RefSeq: NP_009761.4
Others
UniRef100: UniRef100_P38132
UniRef90: UniRef90_P38132
UniRef50: UniRef50_P38132

全选

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研究热度

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