| Type | Description |
|---|---|
| Definition | diacylglycerol kinase zeta |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 11:53:00 | knockdown of DGKZ can induce apoptosis and G2/M phase arrest in human acute myeloid leukemia HL-60 cells through the MAPK/survivin/caspase pathway. | 31288898 |
| 2020-02-15 13:18:00 | we showed that rs7951870-TT genotype was strongly associated with increased DGKZ expression level (P = 0.038). In conclusion, our findings revealed dysregulation of DGKZ in SCZ patients and a significant correction between the gene expression and DGKZ variant rs7951870. | 31087244 |
| 2018-02-24 11:01:00 | Results show that DGKzeta is downregulated in bone marrow mononuclear cells and associated with the severity of aplastic anemia (AA). Also, DGKzeta is a downstream target gene of miR34a. Their dysregulation enhances T-cell activation in AA cells. | 28008152 |
| 2018-01-27 11:16:00 | These results established the positive correlation between DGKzeta expression and gliomagrade. | 26452358 |
| 2017-11-26 00:01:00 | these data suggest that the activation of DGKzeta downstream of antigen recognition provides a mechanism that ensures the activation of PA-dependent signaling as a direct result of the strength of TCR-dependent DAG mobilization. | 27999176 |
| Type | IDs |
|---|---|
| Synonymous | DAGK5, DAGK6, DGK-ZETA, hDGKzeta |
| Gene |
UniProtKB-ID:
DGKZ_HUMAN
UniprotKB:
Q13574
UniParc:
UPI000002ACAE,
UPI0001639B02,
UPI00001C0A01,
UPI000014026C,
UPI0001EB6968,
UPI000013DB71,
UPI0001EB6969
EMBL:
BC041770,
AK300577,
AK124594,
U51477,
AK294888,
CH471064,
U94905,
AC116021,
AK225774
Ensembl:
ENSG00000149091
KO:
hsa:8525
|
| Nucleutide sequences |
EMBL-CDS:
AAH41770.1,
EAW68008.1,
AAB60859.1,
BAC85894.1,
AAC50478.1,
BAH13309.1,
BAH11915.1
Ensembl_TRS:
ENST00000454345,
ENST00000527911,
ENST00000343674,
ENST00000421244,
ENST00000456247,
ENST00000532868,
ENST00000318201
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000412178,
ENSP00000436291,
ENSP00000395684,
ENSP00000436273,
ENSP00000391021,
ENSP00000320340,
ENSP00000343065
RefSeq:
XP_024304508.1,
NP_001186195.1,
XP_024304499.1,
XP_005253239.1,
NP_001099010.1,
XP_024304502.1,
NP_963291.2,
XP_024304507.1,
XP_024304505.1,
XP_016873944.1,
XP_024304497.1,
NP_003637.2,
NP_001186196.1,
XP_024304501.1,
NP_963290.1,
XP_016873945.1,
XP_024304500.1,
XP_024304509.1,
XP_024304498.1,
NP_001186197.1,
XP_024304503.1,
XP_024304504.1,
XP_024304506.1
|
| Others |
UniRef100:
UniRef100_Q13574
UniRef90:
UniRef90_Q13574
UniRef50:
UniRef50_Q13574
UniGene:
Hs.502461
CCDS:
CCDS44580.1,
CCDS41640.1,
CCDS44579.2,
CCDS55758.1,
CCDS7918.1,
CCDS55757.1,
CCDS55759.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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