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852485 GDT1

852485

GDT1

putative ribosome biosynthesis protein GDT1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition putative ribosome biosynthesis protein GDT1

研究结论

Date Results Publications
2019-01-26 12:20:00 obtained first evidence that Gdt1p from yeast directly transports manganese, which strongly reinforces the suggested link between the UPF0016 family and Mn(2+) homeostasis 29632074
2018-07-21 10:34:00 Erd1 transports Pi in the opposite direction from XPR1 and other EXS family proteins and facilitates byproduct removal from the Golgi complex together with Gdt1 29042410
2018-05-26 10:11:00 Gdt1p,to sustain the Golgi glycosylation process, imports Mn(2+) inside the Golgi lumen when Pmr1p exclusively transports Ca(2+). Gdt1p is a Mn(2+)-sensitive protein whose abundance dependents on the kind of the ion transported by Pmr1p. The aspartic residues of the 2 conserved motifs E-x-G-D-[KR], in the cation binding sites of Gdt1p, play a role in Golgi glycosylation and hence in Mn(2+)/Ca(2+)transport. 29108953
2017-03-04 12:46:00 Gdt1p controls cellular calcium stores and plays a major role in the calcium response induced by osmotic shock when the Golgi calcium pump, Pmr1p, is absent. Furthermore, in the presence of a high concentration of external calcium, Gdt1p is required for glycosylation of carboxypeptidase Y and the glucanosyltransferase Gas1p. 27075443

名称对应

Type IDs
Gene
UniProtKB-ID: GDT1_YEAST
UniprotKB: P38301
UniParc: UPI000013A20B
EMBL: Z36057, U02073, AY558567, Z36056, BK006936
EnsemblGenome: YBR187W
KO: sce:YBR187W
Nucleutide sequences
EMBL-CDS: CAA85150.1, DAA07302.1, CAA85148.1, AAS56893.1, AAB60282.1
Gene_ORFName: YBR1310
EnsemblGenome_TRS: YBR187W_mRNA
Protein sequencees
EnsemblGenome_PRO: YBR187W
RefSeq: NP_009746.1
Others
UniRef100: UniRef100_P38301
UniRef90: UniRef90_P38301
UniRef50: UniRef50_P38301

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