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852440 SUP45

852440

SUP45

translation termination factor eRF1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition translation termination factor eRF1

研究结论

Date Results Publications
2021-01-02 12:53:00 The catalytic activity of the translation termination factor methyltransferase Mtq2-Trm112 complex is required for large ribosomal subunit biogenesis. 33166396
2019-11-30 10:12:00 Defects in the Dbp5-guided eRF1 delivery lead to premature contact and premature dissociation of eRF1 and eRF3 from the ribosome and to subsequent stop codon readthrough. Thus, the stepwise Dbp5-controlled termination complex assembly is essential for regular translation termination events 30873535
2019-06-29 10:20:00 The study used analytical ultracentrifugation with fluorescent detection system to identify the protein complexome of eRF1 in Saccharomyces cerevisiae. In addition to eRF1 presence in translating polysomes, the study found that eRF1 is associated with five other macromolecular complexes: 77S, 57S, 39S, 28S, and 20S in size. 29139201
2017-05-13 21:50:00 We demonstrated that interaction of [SWI+] and [PIN+] causes inactivation of SUP45 gene that leads to nonsense suppression. Our data show that prion interactions may cause heritable traits in Saccharomyces cerevisiae. 28027291
2016-02-27 11:00:00 In this work, the authors show that nonsense and missense mutations in the SUP45, but not the SUP35, gene abolish diploid pseudohyphal and haploid invasive growth. 26054854

名称对应

Type IDs
Synonymous SAL4, SUP1, SUP47
Gene
UniProtKB-ID: ERF1_YEAST
UniprotKB: P12385
UniParc: UPI0000052FB8
EMBL: BK006936, X73531, M28042, X04082, Z36012
EnsemblGenome: YBR143C
KO: sce:YBR143C
Nucleutide sequences
EMBL-CDS: CAA27719.1, DAA07259.1, CAA51935.1, CAA85101.1
Gene_ORFName: YBR1120
EnsemblGenome_TRS: YBR143C_mRNA
Protein sequencees
EnsemblGenome_PRO: YBR143C
RefSeq: NP_009701.3
Others
UniRef100: UniRef100_P12385
UniRef90: UniRef90_P12385
UniRef50: UniRef50_P12385

全选

研究热度
发表文献
研究结论
热点单位
排名 科研单位 文献
1

University of Kent

5
2

University of Toronto

3
3

University of Wisconsin-Madison

3
4

University of California

3
5

Institut für Mikrobiologie und Genetik

3
热点人员
排名 研究人员 文献
1

M D Ter-Avanesyan

5
2

Valérie Heurgué-Hamard

5
3

Heike Krebber

4
4

S V Paushkin

4
5

V V Kushnirov

4
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